ZFIN ID: ZDB-GENE-021008-1
Gene Name: forkhead box N1
Gene Symbol: foxn1

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Previous Names: nude (1), whnb (1)

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(Including Attributions)
Location: Chr: 15 Mapping Details/Browsers
GENE EXPRESSION
All Expression Data: 22 figures from 20 publications
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Juvenile:Days 45-89 (45d-90d, 14 mm, 12 teeth)
  anatomical structure, pharyngeal arch, pharyngeal arch 3-7 skeleton, thymic epithelium (all 9) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa35901 Point Mutation Unknown Premature Stop ENU
Targeting reagents: MO1-foxn1 (1), MO2-foxn1 (1), MO3-foxn1 (1)
PHENOTYPE
Data: 2 figures from 2 publications
Observed in: thymus cell proliferation, thymus epithelial cell, thymus, thymus development
DISEASE ASSOCIATED WITH foxn1 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
T-cell immunodeficiency, congenital alopecia, and nail dystrophy T-cell immunodeficiency, congenital alopecia, and nail dystrophy 601705
GENE ONTOLOGY
Ontology GO Term
Biological Process thymus development (more)
Cellular Component nucleus (more)
Molecular Function transcription regulatory region sequence-specific DNA binding (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001766 (1)
  • InterPro:IPR011991 (1)
  • InterPro:IPR030456 (1)
  • PROSITE:PS00658 (1)
  • PROSITE:PS50039 (1)
  • Pfam:PF00250 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA foxn1-001 (1) 2718
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM foxn1
    TgBAC(foxn1:mCherry)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    foxn1Contained in: [BAC] DKEY-234F12 (1) (order this)
    foxn1Encodes: [cDNA] MGC:193870 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212573 (1) 1911bp
    Genomic GenBank:BX663513 (1) 249413bp Blast at MegaBLAST
    Polypeptide UniProtKB:B3DH11 (1) 565aa
    Sequence Clusters UniGene:30207 (1)
    Sequence Information (all 15)
    OTHER foxn1 GENE PAGES
  • Gene:266748 (1)
  • VEGA:OTTDARG00000020765 (1)
  • Ensembl(GRCz10):ENSDARG00000011879 (1)
  • ORTHOLOGY for foxn1 (Chr: 15)
    CITATIONS (43)