ZFIN ID: ZDB-GENE-020809-1
Gene Name: roundabout, axon guidance receptor, homolog 4 (Drosophila)
Gene Symbol: robo4
Sequence Ontology ID : SO:0000704

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Previous Names: sc:d0823, wu:fa16f09

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(Including Attributions)
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
GENE EXPRESSION
All Expression Data: 19 figures from 9 publications
Directly Submitted Expression Data: 6 figures (24 images) from Thisse et al., 2008 [cssl:d823]
Wild-type Stages, Structures: Gastrula:75%-epiboly (8.0h-9.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6175 Point Mutation Unknown Premature Stop ENU
sa8702 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21760 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24878 Point Mutation Unknown Premature Stop ENU
    sa38805 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: Fig. 3 from Fish et al., 2011
    Observed in:
    DISEASE ASSOCIATED WITH robo4 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH robo4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process endothelial cell migration (more)
    Cellular Component intrinsic component of plasma membrane (more)
    Molecular Function molecular_function (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003598 (1)
  • InterPro:IPR003599 (1)
  • InterPro:IPR003961 (1)
  • InterPro:IPR007110 (1)
  • InterPro:IPR013098 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR036116 (1)
  • InterPro:IPR036179 (1)
  • PROSITE:PS50835 (1)
  • PROSITE:PS50853 (1)
  • Pfam:PF00041 (1)
  • Pfam:PF07679 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA robo4-001 (1) 3715
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM robo4 No data available
    MARKER RELATIONSHIPS
    robo4Contained in: [BAC] CH211-164N21 (1) (order this), DKEY-30J19 (1) (order this)
    robo4Contains: [SNP] rs3728312 (1), rs3728313 (1)
    robo4Encodes: [EST] fa16f09 (1)
    [cDNA] cssl:d823 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005172710 (1)
    Genomic GenBank:AL845320 (1) 183417bp
    Select Tool
    Polypeptide UniProtKB:F1RE66 (1) 1134aa
    Sequence Clusters UniGene:75958 (1)
    Sequence Information (all 25)
    OTHER robo4 GENE PAGES
  • Alliance (1)
  • Gene:560765 (1)
  • VEGA:OTTDARG00000008425 (1)
  • Ensembl(GRCz11):ENSDARG00000009387 (2)
  • ORTHOLOGY for robo4 (Chr: 10)
    CITATIONS (33)