ZFIN ID: ZDB-GENE-020808-1
Gene Name: ceramide synthase 4a
Gene Symbol: cers4a    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: trh1

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have sphingosine N-acyltransferase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to localize to endoplasmic reticulum. Is expressed in several structures, including brain; digestive system; otic vesicle; pronephros; and tail bud. Orthologous to human CERS4 (ceramide synthase 4).
Genome Resources: Alliance (1),  Gene:259250 (1),  Ensembl(GRCz11):ENSDARG00000031387 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:92553]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa43758 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cers4a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cers4a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ceramide biosynthetic process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function DNA binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cers4a-201 (1)    Ensembl 1869
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cers4a No data available
    MARKER RELATIONSHIPS
    cers4a Contained in: [BAC] DKEY-241F21 (1) (order this)
    cers4a Encodes: [cDNA] MGC:92553 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_153670 (1) 1876 nt
    Genomic GenBank:CR751224 (1) 151612 nt
    Select Tool
    Polypeptide UniProtKB:Q1L8N1 (1) 407 aa
    Sequence Information (all 13)
    ORTHOLOGY for cers4a ( Chr: 22 )
    CITATIONS (28)