ZFIN is now using GRCz12tu for Genomic Data
Gene
thbs3a
- ID
- ZDB-GENE-020708-3
- Name
- thrombospondin 3a
- Symbol
- thbs3a Nomenclature History
- Previous Names
-
- thbs3
- Tsp-3a (1)
- zgc:103461
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable calcium ion binding activity. Acts upstream of or within mesenchymal to epithelial transition and somite development. Predicted to be located in extracellular region. Predicted to be active in collagen-containing extracellular matrix. Is expressed in several structures, including brain; ectoderm; epidermis; heart; and pectoral fin. Orthologous to human THBS3 (thrombospondin 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103461 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018097 | EGF-like calcium-binding, conserved site |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001881 | EGF-like calcium-binding domain |
| Domain | IPR008859 | Thrombospondin, C-terminal |
| Domain | IPR024665 | Thrombospondin/cartilage oligomeric matrix protein, coiled-coil domain |
| Domain | IPR048287 | Thrombospondin-like, N-terminal domain |
| Domain | IPR049883 | NOTCH1 EGF-like calcium-binding domain |
| Homologous_superfamily | IPR009030 | Growth factor receptor cysteine-rich domain superfamily |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR028974 | TSP type-3 repeat |
| Homologous_superfamily | IPR046970 | Thrombospondin/cartilage oligomeric matrix protein, coiled-coil domain superfamily |
| Repeat | IPR003367 | Thrombospondin, type 3-like repeat |
| Repeat | IPR017897 | Thrombospondin, type 3 repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | Concanavalin A-like lectin/glucanase domain superfamily | EGF-like calcium-binding, conserved site | EGF-like calcium-binding domain | EGF-like domain | Growth factor receptor cysteine-rich domain superfamily | NOTCH1 EGF-like calcium-binding domain | Thrombospondin/cartilage oligomeric matrix protein, coiled-coil domain | Thrombospondin/cartilage oligomeric matrix protein, coiled-coil domain superfamily | Thrombospondin, C-terminal | Thrombospondin-like, N-terminal domain | Thrombospondin, type 3-like repeat | Thrombospondin, type 3 repeat | TSP type-3 repeat |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q8JHW2 | InterPro | 962 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
thbs3a-201
(1)
|
Ensembl | 3,279 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers