Gene
thbs2a
- ID
- ZDB-GENE-020708-2
- Name
- thrombospondin 2a
- Symbol
- thbs2a Nomenclature History
- Previous Names
-
- thbs2
- Tsp-2 (1)
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have calcium ion binding activity. Predicted to be involved in negative regulation of angiogenesis. Predicted to localize to collagen-containing extracellular matrix. Orthologous to human THBS2 (thrombospondin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Lumbar disc herniation, susceptibility to} | 603932 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001007 | VWFC domain |
| Domain | IPR001881 | EGF-like calcium-binding domain |
| Domain | IPR008859 | Thrombospondin, C-terminal |
| Domain | IPR024731 | EGF domain |
| Domain | IPR048287 | Thrombospondin-like, N-terminal domain |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR028974 | TSP type-3 repeat |
| Homologous_superfamily | IPR036383 | Thrombospondin type-1 (TSP1) repeat superfamily |
| Repeat | IPR000884 | Thrombospondin type-1 (TSP1) repeat |
| Repeat | IPR003367 | Thrombospondin, type 3-like repeat |
| Repeat | IPR017897 | Thrombospondin, type 3 repeat |
Domain Details Per Protein
| Protein | Length | Concanavalin A-like lectin/glucanase domain superfamily | EGF domain | EGF-like calcium-binding domain | EGF-like domain | Thrombospondin, C-terminal | Thrombospondin-like, N-terminal domain | Thrombospondin type-1 (TSP1) repeat | Thrombospondin type-1 (TSP1) repeat superfamily | Thrombospondin, type 3-like repeat | Thrombospondin, type 3 repeat | TSP type-3 repeat | VWFC domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F8W5Z7
|
1175 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
thbs2a-202
(1)
|
Havana | 4923 nt |
Interactions and Pathways
No data available
Plasmids
No data available