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ZIRC
ZFIN ID: ZDB-GENE-020503-3
Gene Name: insulin receptor a
Gene Symbol: insra
Sequence Ontology ID : SO:0000704

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Previous Name: IRa (1)

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(Including Attributions)
Location: Chr: 2 Mapping Details/Browsers
AUTOMATED DESCRIPTION
Predicted to have insulin receptor substrate binding activity and insulin-activated receptor activity. Involved in chordate embryonic development and developmental growth. Predicted to localize to  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb357 Indel Unknown Unknown TALEN
la014939Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la023659Tg Transgenic Insertion Unknown Unknown DNA
    psi101 Point Mutation Exon 3 Missense CRISPR
    sa1682 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa6016 Point Mutation Unknown Premature Stop ENU
    sa32968 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH insra HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Donohue syndrome Leprechaunism 246200
    familial hyperinsulinemic hypoglycemia 5 Hyperinsulinemic hypoglycemia, familial, 5 609968
    Diabetes mellitus, insulin-resistant, with acanthosis nigricans 610549
    Rabson-Mendenhall syndrome 262190
    DISEASE ASSOCIATED WITH insra VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process chordate embryonic development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 27)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA insra-002 (1) 784
    mRNA insra-201 (1) 6191
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM insra No data available
    MARKER RELATIONSHIPS
    insraContained in: [BAC] DKEY-57K2 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001142672 (1) 6219bp
    Genomic GenBank:BX539340 (1) 234470bp Blast at MegaBLAST
    Polypeptide UniProtKB:B7SNG4 (1) 1353aa
    Sequence Clusters UniGene:85773 (1)
    Sequence Information (all 17)
    ORTHOLOGY for insra (Chr: 2)
    CITATIONS (60)