ZFIN ID: ZDB-GENE-020430-3
Gene Name: flotillin 2a
Gene Symbol: flot2a    Nomenclature History

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Previous Names: fb48a04 (1), im:7143869, reggie-1a (1), wu:fb48a04 (1), zgc:55821 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Involved in regulation of cell-cell adhesion mediated by cadherin and regulation of epiboly involved in gastrulation with mouth forming second. Predicted to localize to endocytic vesicle and endosome. Is expressed in several structures, including fin; nervous system; pectoral fin bud; segmental plate; and trigeminal placode. Orthologous to human FLOT2 (flotillin 2).
Genome Resources: Alliance (1),  Gene:245698 (1),  Ensembl(GRCz11):ENSDARG00000004830 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la025092Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la025094Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-flot2a
    1
    MO1-flot2a N/A 1
    MO2-flot2a N/A 1
    MO3-flot2a N/A 1
    MO4-flot2a N/A 1
    DISEASE ASSOCIATED WITH flot2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH flot2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of cell-cell adhesion mediated by cadherin (more)
    Cellular Component endocytic vesicle (more)
    Molecular Function molecular_function (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    aberrant processed transcript flot2a-202 (1)    Ensembl 544
    mRNA flot2a-201 (1)    Ensembl 2014
    ncRNA flot2a-003 (1)    Ensembl 647
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM flot2a No data available
    MARKER RELATIONSHIPS
    flot2a Contained in: [BAC] DKEY-210G19 (1) (order this)
    flot2a Encodes: [EST] fb48a04, IMAGE:7143869 (1)
    [cDNA] MGC:55821, MGC:193094 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_213075 (1) 3054 nt
    Genomic GenBank:BX323596 (1) 251428 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q98TZ8 (1) 428 aa
    Sequence Information (all 25)
    ORTHOLOGY for flot2a ( Chr: 5 )
    CITATIONS (37)