ZFIN ID: ZDB-GENE-020423-5
Gene Name: follicle stimulating hormone receptor
Gene Symbol: fshr
Sequence Ontology ID : SO:0000704

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Previous Names: gonadotropic hormone I (1), GTHR-I (1), zfGTHR-I

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(Including Attributions)
Location: Chr: 12 Mapping Details/Browsers
AUTOMATED DESCRIPTION
Exhibits follicle-stimulating hormone receptor activity; involved in male gonad development, ovarian follicle development, and spermatogenesis; predicted to localize to the integral component of  ...
GENE EXPRESSION
All Expression Data: 13 figures from 10 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu86]
Wild-type Stages, Structures: Juvenile:Days 45-89 (45d-90d, 14 mm, 12 teeth) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa13419 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42035 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • umo3 Small Deletion Unknown Frameshift TALEN
    zf687 Small Deletion Exon 2 Frameshift, Premature Stop TALEN
    Targeting reagents:
    PHENOTYPE
    Data: 7 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH fshr HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    ovarian dysgenesis 1 Ovarian dysgenesis 1 233300
    ovarian hyperstimulation syndrome Ovarian hyperstimulation syndrome 608115
    Ovarian response to FSH stimulation 276400
    DISEASE ASSOCIATED WITH fshr VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process female gonad development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function follicle-stimulating hormone receptor activity (more)
    GO Terms (all 20)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000276 (1)
  • InterPro:IPR001611 (1)
  • InterPro:IPR002131 (1)
  • InterPro:IPR002272 (1)
  • InterPro:IPR002274 (1)
  • InterPro:IPR017452 (1)
  • InterPro:IPR026906 (1)
  • InterPro:IPR032675 (1)
  • InterPro:IPR034298 (1)
  • PROSITE:PS00237 (1)
  • PROSITE:PS50262 (1)
  • Pfam:PF00001 (1)
  • Pfam:PF13306 (1)
  • Pfam:PF13855 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA fshr-201 (1) 2543
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM fshr No data available
    MARKER RELATIONSHIPS
    fshrContained in: [BAC] DKEY-25M3 (1) (order this)
    fshrEncodes: [EST] eu86 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001001812 (1) 2543bp
    Genomic GenBank:BX677665 (1) 136144bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8RSR3 (1) 668aa
    Sequence Clusters UniGene:80713 (1)
    Sequence Information (all 13)
    OTHER fshr GENE PAGES
  • Alliance (1)
  • Gene:195820 (1)
  • VEGA:OTTDARG00000027379 (1)
  • ORTHOLOGY for fshr (Chr: 12)
    CITATIONS (94)