ZFIN ID: ZDB-GENE-020402-1
Gene Name: glycine receptor, alpha 3
Gene Symbol: glra3    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Exhibits extracellularly glycine-gated ion channel activity. Predicted to be involved in ion transmembrane transport. Predicted to localize to integral component of plasma membrane. Is expressed in hindbrain and spinal cord. Orthologous to human GLRA3 (glycine receptor alpha 3).
Genome Resources: Alliance (1),  Gene:192124 (1),  Ensembl(GRCz11):ENSDARG00000011066 (1)
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa18125 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32718 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • udm107 Small Deletion Unknown Unknown CRISPR
    zko722a Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-glra3 1
    CRISPR2-glra3 1
    MO1-glra3 N/A 1
    PHENOTYPE
    Data: Fig. 4 from Hirata et al., 2013
    Observed in:
    DISEASE ASSOCIATED WITH glra3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH glra3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ion transmembrane transport (more)
    Cellular Component integral component of membrane (more)
    Molecular Function extracellularly glycine-gated ion channel activity (more)
    GO Terms (all 25)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM glra3 No data available
    MARKER RELATIONSHIPS
    glra3 Encodes: [cDNA] MGC:195049 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_152965 (1) 2376 nt
    Genomic GenBank:CU929406 (1) 32669 nt
    Select Tool
    Polypeptide UniProtKB:B3DJL8 (1) 450 aa
    Sequence Information (all 23)
    ORTHOLOGY for glra3 ( Chr: 1 )
    CITATIONS (23)