Gene
gria2a
- ID
- ZDB-GENE-020125-3
- Name
- glutamate receptor, ionotropic, AMPA 2a
- Symbol
- gria2a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have AMPA glutamate receptor activity. Involved in several processes, including embryonic cranial skeleton morphogenesis; mechanosensory lateral line system development; and neural crest cell development. Predicted to localize to AMPA glutamate receptor complex and dendritic spine. Is expressed in nervous system. Orthologous to human GRIA2 (glutamate ionotropic receptor AMPA type subunit 2).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 12 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu675 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Li et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Neurodevelopmental disorder with language impairment and behavioral abnormalities | 618917 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001320 | Ionotropic glutamate receptor, C-terminal |
Domain | IPR001638 | Solute-binding protein family 3/N-terminal domain of MltF |
Domain | IPR001828 | Receptor, ligand binding region |
Domain | IPR019594 | Ionotropic glutamate receptor, L-glutamate and glycine-binding domain |
Family | IPR001508 | Ionotropic glutamate receptor, metazoa |
Family | IPR015683 | Ionotropic glutamate receptor |
Homologous_superfamily | IPR028082 | Periplasmic binding protein-like I |
Domain Details Per Protein
Protein | Length | Ionotropic glutamate receptor | Ionotropic glutamate receptor, C-terminal | Ionotropic glutamate receptor, L-glutamate and glycine-binding domain | Ionotropic glutamate receptor, metazoa | Periplasmic binding protein-like I | Receptor, ligand binding region | Solute-binding protein family 3/N-terminal domain of MltF |
---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M2BI34
|
893 | |||||||
UniProtKB:A0A8M2BIL5
|
893 | |||||||
UniProtKB:Q71E63
|
875 | |||||||
UniProtKB:A0A8M2BI57
|
875 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
gria2a-201
(1)
|
Havana | 1044 nt | |
mRNA |
gria2a-202
(1)
|
Havana | 3334 nt |
Interactions and Pathways
No data available
Plasmids
No data available