Gene
s1pr2
- ID
- ZDB-GENE-020123-2
- Name
- sphingosine-1-phosphate receptor 2
- Symbol
- s1pr2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have sphingosine-1-phosphate receptor activity. Involved in several processes, including embryonic morphogenesis; sensory organ development; and sphingosine-1-phosphate receptor signaling pathway. Predicted to localize to cytoplasm and plasma membrane. Is expressed in several structures, including cardiovascular system; midbrain hindbrain boundary neural rod; midbrain hindbrain boundary neural tube; nervous system; and pleuroperitoneal region. Used to study carcinoma. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 68. Orthologous to human S1PR2 (sphingosine-1-phosphate receptor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 17 figures from 12 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu461 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- 45 figures from 25 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive nonsyndromic deafness 68 | Alliance | Deafness, autosomal recessive 68 | 610419 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| carcinoma | s1pr2m93/m93 | standard conditions | Gu et al., 2015 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Sphingosine 1-phosphate receptor |
|---|---|---|---|---|
|
UniProtKB:Q9I8K8
|
370 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available