Gene

pknox1.2

ID
ZDB-GENE-020123-1
Name
pbx/knotted 1 homeobox 1.2
Symbol
pknox1.2 Nomenclature History
Previous Names
  • prep1.2
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in pharyngeal system development and retinoic acid receptor signaling pathway. Predicted to localize to nuclear chromatin. Is expressed in brain; head; neural tube; and pectoral fin. Orthologous to human PKNOX1 (PBX/knotted 1 homeobox 1).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Vaccari et al., 2010
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pknox1.2 Human Ortholog
No data available
Associated With pknox1.2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001356 Homeobox domain
Domain IPR008422 Homeobox KN domain
Domain IPR032453 Homeobox protein PKNOX/Meis, N-terminal
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox domain Homeobox KN domain Homeobox-like domain superfamily Homeobox protein PKNOX/Meis, N-terminal
UniProtKB:B8A551 402
UniProtKB:Q90XG8 207
UniProtKB:E7FBG0 445
UniProtKB:Q804R7 335
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations