Gene

ptprfa

ID
ZDB-GENE-020107-2
Name
protein tyrosine phosphatase receptor type Fa
Symbol
ptprfa Nomenclature History
Previous Names
  • LAR (1)
  • ptprf
  • zf-LAR (1)
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have protein tyrosine phosphatase activity. Involved in sensory neuron axon guidance. Predicted to localize to integral component of membrane. Is expressed in nervous system; pectoral fin; pharyngeal arch; and somite. Human ortholog(s) of this gene implicated in hyperinsulinism. Orthologous to human PTPRF (protein tyrosine phosphatase receptor type F).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ptprfa Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Breasts and/or nipples, aplasia or hypoplasia of, 2 616001
Associated With ptprfa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR016130 Protein-tyrosine phosphatase, active site
Domain IPR000242 Tyrosine-specific protein phosphatase, PTPase domain
Domain IPR000387 Tyrosine-specific protein phosphatases domain
Domain IPR003595 Protein-tyrosine phosphatase, catalytic
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin subtype
Domain IPR003961 Fibronectin type III
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013098 Immunoglobulin I-set
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR029021 Protein-tyrosine phosphatase-like
Homologous_superfamily IPR036116 Fibronectin type III superfamily
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length Fibronectin type III Fibronectin type III superfamily Immunoglobulin I-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype Immunoglobulin subtype 2 Protein-tyrosine phosphatase, active site Protein-tyrosine phosphatase, catalytic Protein-tyrosine phosphatase-like Tyrosine-specific protein phosphatase, PTPase domain Tyrosine-specific protein phosphatases domain
UniProtKB:A0A8M9PLU1 1903
UniProtKB:A0A8M9PZG0 1802
UniProtKB:A0A8M9QF59 1908
UniProtKB:A0A8M9PZF5 1816
UniProtKB:A0A8M9QA39 1918
UniProtKB:A0A8M9QF62 1806
UniProtKB:A0A8M9Q5Y4 1812
UniProtKB:A0A8M9PLU6 1808
UniProtKB:H9CWQ2 1894
UniProtKB:A0A8M9Q5Y1 1912
UniProtKB:A0A8M9PLT7 1914
UniProtKB:A0A8M9QA48 1791
UniProtKB:A0A8M9QA45 1907
UniProtKB:A0A8M9PZE9 1914
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations