Gene
ptprfa
- ID
- ZDB-GENE-020107-2
- Name
- protein tyrosine phosphatase receptor type Fa
- Symbol
- ptprfa Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have protein tyrosine phosphatase activity. Involved in sensory neuron axon guidance. Predicted to localize to integral component of membrane. Is expressed in nervous system; pectoral fin; pharyngeal arch; and somite. Human ortholog(s) of this gene implicated in hyperinsulinism. Orthologous to human PTPRF (protein tyrosine phosphatase receptor type F).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Breasts and/or nipples, aplasia or hypoplasia of, 2 | 616001 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR016130 | Protein-tyrosine phosphatase, active site |
| Domain | IPR000242 | Tyrosine-specific protein phosphatase, PTPase domain |
| Domain | IPR000387 | Tyrosine-specific protein phosphatases domain |
| Domain | IPR003595 | Protein-tyrosine phosphatase, catalytic |
| Domain | IPR003598 | Immunoglobulin subtype 2 |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR003961 | Fibronectin type III |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013098 | Immunoglobulin I-set |
| Family | IPR050713 | Receptor-type Tyrosine-protein Phosphatases/Ushers |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR029021 | Protein-tyrosine phosphatase-like |
| Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin domain subtype | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype 2 | Protein-tyrosine phosphatase, active site | Protein-tyrosine phosphatase, catalytic | Protein-tyrosine phosphatase-like | Receptor-type Tyrosine-protein Phosphatases/Ushers | Tyrosine-specific protein phosphatase, PTPase domain | Tyrosine-specific protein phosphatases domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PLU1
|
1903 | ||||||||||||||
|
UniProtKB:A0A8M9PZG0
|
1802 | ||||||||||||||
|
UniProtKB:A0A8M9QF59
|
1908 | ||||||||||||||
|
UniProtKB:A0A8M9PZF5
|
1816 | ||||||||||||||
|
UniProtKB:A0A8M9QA39
|
1918 | ||||||||||||||
|
UniProtKB:A0A8M9QF62
|
1806 | ||||||||||||||
|
UniProtKB:A0A8M9Q5Y4
|
1812 | ||||||||||||||
|
UniProtKB:A0A8M9PLU6
|
1808 | ||||||||||||||
|
UniProtKB:H9CWQ2
|
1894 | ||||||||||||||
|
UniProtKB:A0A8M9Q5Y1
|
1912 | ||||||||||||||
|
UniProtKB:A0A8M9PLT7
|
1914 | ||||||||||||||
|
UniProtKB:A0A8M9QA48
|
1791 | ||||||||||||||
|
UniProtKB:A0A8M9QA45
|
1907 | ||||||||||||||
|
UniProtKB:A0A8M9PZE9
|
1914 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ptprfa-202
(1)
|
Ensembl | 4,041 nt | ||
| mRNA |
ptprfa-203
(1)
|
Ensembl | 8,712 nt | ||
| mRNA |
ptprfa-204
(1)
|
Ensembl | 5,988 nt | ||
| mRNA |
ptprfa-205
(1)
|
Ensembl | 5,682 nt | ||
| mRNA |
ptprfa-206
(1)
|
Ensembl | 8,750 nt | ||
| mRNA |
ptprfa-207
(1)
|
Ensembl | 8,432 nt | ||
| mRNA |
ptprfa-208
(1)
|
Ensembl | 8,738 nt | ||
| ncRNA |
ptprfa-002
(1)
|
Ensembl | 747 nt |
Interactions and Pathways
No data available
Plasmids