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ZIRC
ZFIN ID: ZDB-GENE-011212-1
Gene Name: fatty acid desaturase 2
Gene Symbol: fads2    Nomenclature History

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Previous Names: Fadsd6 (1), DRD5/D6 (1), wu:fb64c04, wu:fb69e08, zgc:112502

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have linoleoyl-CoA desaturase activity. Involved in liver development. Predicted to localize to the endoplasmic reticulum; endoplasmic reticulum membrane; and integral component of membrane. Is expressed in several structures, including alar plate midbrain region; fat cell; nervous system; optic vesicle; and pleuroperitoneal region. Orthologous to several human genes including FADS2 (fatty acid desaturase 2).
Genome Resources: Alliance (1),  Gene:140615 (1),  Ensembl(GRCz11):ENSDARG00000019532 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb219 Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • ihb220 Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • zf2026 Small Deletion Unknown Frameshift, Premature Stop TALEN
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-fads2 1
    MO1-fads2 N/A 1
    MO2-fads2 N/A 1
    TALEN1-fads2 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH fads2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH fads2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process liver development (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function linoleoyl-CoA desaturase activity (more)
    GO Terms (all 12)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA fads2-201 (1)    Ensembl 1666
    fads2-202 (1)    Ensembl 1597
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fads2 No data available
    MARKER RELATIONSHIPS
    fads2 Contained in: [BAC] CH73-273G8 (1) (order this)
    fads2 Contains: [SSLP] z975
    fads2 Encodes: [EST] fb64c04 (1), fb69e08
    [cDNA] MGC:56438 (1) (order this), MGC:171535 (1) (order this), MGC:173924 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131645 (1) 1708 bp
    Genomic GenBank:CU694371 (1) 83266 bp
    Select Tool
    Polypeptide UniProtKB:F1R3G9 (1) 444 aa
    Sequence Clusters UniGene:75661 (1)
    Sequence Information (all 29)
    ORTHOLOGY for fads2 ( Chr: 25 )
    CITATIONS (61)