ZFIN ID: ZDB-GENE-011210-1
Gene Name: caspase 3, apoptosis-related cysteine peptidase a
Gene Symbol: casp3a
Sequence Ontology ID : SO:0000704

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Previous Names: casp3, zgc:100890

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Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 26 figures from 18 publications
Directly Submitted Expression Data: 6 figures (14 images) from Thisse et al., 2005 [eu109]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  axis, central nervous system, epiphysis, eye (all 17) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
zko331a Small Deletion Unknown Unknown CRISPR
Targeting reagents: MO1-casp3a (1)
PHENOTYPE
Data: 4 figures from 2 publications
Observed in: epiboly involved in gastrulation with mouth forming second, retinal ganglion cell axon, retinal ganglion cell axon collateral, retinal ganglion cell collateral sprouting in absence of injury (all 7) expand
DISEASE ASSOCIATED WITH casp3a HUMAN ORTHOLOGNo data available
GENE ONTOLOGY
Ontology GO Term
Biological Process apoptotic process (more)
Cellular Component cytoplasm (more)
Molecular Function peptidase activity (more)
GO Terms (all 15)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001309 (1)
  • InterPro:IPR002138 (1)
  • InterPro:IPR015470 (1)
  • InterPro:IPR015917 (1)
  • InterPro:IPR016129 (1)
  • InterPro:IPR029030 (1)
  • InterPro:IPR033139 (1)
  • PROSITE:PS01121 (1)
  • PROSITE:PS01122 (1)
  • PROSITE:PS50207 (1)
  • PROSITE:PS50208 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA casp3a-001 (1) 2918
    casp3a-002 (1) 792
    casp3a-003 (1) 862
    casp3a-004 (1) 471
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM casp3a
    Tg(5xUAS:casp3a,5xUAS:Hsa.HIST1H2BJ-Citrine,cryaa:RFP), Tg(CMV:casp3a,CMV:GFP), Tg(UAS:casp3a-UTR-nanos3,CMV:EGFP)
    MARKER RELATIONSHIPS
    casp3aContained in: [BAC] CH211-197N1 (1) (order this), DKEY-228C11 (1) (order this)
    casp3aEncodes: [EST] eu109 (1)
    [cDNA] MGC:100890 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131877 (1) 2950bp
    Genomic GenBank:BX537280 (1) 163151bp
    Select Tool
    Polypeptide UniProtKB:A0A1C9CJ76 (1) 282aa
    Sequence Clusters UniGene:11726 (1)
    Sequence Information (all 19)
    OTHER casp3a GENE PAGES
  • Alliance (1)
  • Gene:140621 (1)
  • VEGA:OTTDARG00000019444 (1)
  • Ensembl(GRCz10):ENSDARG00000017905 (1)
  • ORTHOLOGY for casp3a (Chr: 1)
    CITATIONS (97)