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Gene

mt-nd5

ID
ZDB-GENE-011205-12
Name
NADH dehydrogenase 5, mitochondrial
Symbol
mt-nd5 Nomenclature History
Previous Names
  • mtnd5 (1)
  • ND5 (1)
Type
protein_coding_gene
Location
Chr: MT Mapping Details/Browsers
Description
Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in electron transport coupled proton transport; mitochondrial electron transport, NADH to ubiquinone; and mitochondrial respiratory chain complex I assembly. Predicted to act upstream of or within ATP synthesis coupled electron transport. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; Leigh disease; and MELAS syndrome. Orthologous to human MT-ND5 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mt-nd5 Human Ortholog
No data available
Associated With mt-nd5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal
Domain IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit
Domain IPR010934 NADH dehydrogenase subunit 5, C-terminal
Family IPR003945 NADH-plastoquinone oxidoreductase, chain 5
Domain Details Per Protein
Protein Length NADH dehydrogenase subunit 5, C-terminal NADH-plastoquinone oxidoreductase, chain 5 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal
UniProtKB:Q9MIY0 606
Transcripts
Genome Browsers
No data available
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations