ZFIN ID: ZDB-GENE-011003-1
Gene Name: alcohol dehydrogenase 5
Gene Symbol: adh5    Nomenclature History

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Previous Names: ADH3 (1), fb60b11, gsnor (1), wu:fb60b11

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have S-(hydroxymethyl)glutathione dehydrogenase activity; alcohol dehydrogenase activity, zinc-dependent; and zinc ion binding activity. Predicted to be involved in formaldehyde catabolic process. Predicted to localize to cytosol. Is expressed in several structures, including blastodisc; central nervous system; digestive system; pleuroperitoneal region; and trunk. Human ortholog(s) of this gene implicated in asthma. Orthologous to human ADH5 (alcohol dehydrogenase 5 (class III), chi polypeptide).
Genome Resources: Alliance (1),  Gene:116517 (1),  Ensembl(GRCz11):ENSDARG00000080010 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-adh5 N/A 1
PHENOTYPE
Data: Fig. 3 from Cox et al., 2014
Observed in:
DISEASE ASSOCIATED WITH adh5 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH adh5 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process ethanol oxidation (more)
Cellular Component cytosol (more)
Molecular Function metal ion binding (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA adh5-201 (1)    Ensembl 1325
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM adh5 No data available
MARKER RELATIONSHIPS
adh5 Contained in: [BAC] CH73-36J8 (1)
adh5 Encodes: [EST] fb60b11
[cDNA] MGC:77553 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_131849 (1) 1316 nt
Genomic GenBank:CU467639 (1) 118056 nt
Select Tool
Polypeptide UniProtKB:Q6NXA6 (1) 376 aa
Sequence Information (all 13)
ORTHOLOGY for adh5 ( Chr: 14 )
CITATIONS (35)