ZFIN ID: ZDB-GENE-010919-1
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Gene Name: microphthalmia-associated transcription factor b
Gene Symbol: mitfb
Sequence Ontology ID : SO:0000704

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Previous Name: Mitf1 (1)

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(Including Attributions)
Location: Chr: 23 Mapping Details/Browsers
Note: Accession AF362683 is chimeric.
GENE EXPRESSION
All Expression Data: 5 figures from 4 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu230]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
  epiphysis, melanocyte, olfactory bulb, optic cup pigmented epithelial cell (all 7) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu3857 Point Mutation Unknown Unknown ENU
sa11609 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa25188 Point Mutation Unknown Premature Stop ENU
    sa43899 Point Mutation Unknown Splice Site ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH mitfb HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    ocular albinism with sensorineural deafness Waardenburg syndrome/ocular albinism, digenic 103470
    skin melanoma {Melanoma, cutaneous malignant, susceptibility to, 8} 614456
    Tietz syndrome Tietz albinism-deafness syndrome 103500
    Waardenburg syndrome type 2A Waardenburg syndrome, type 2A 193510
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process transcription, DNA-templated (more)
    Cellular Component nucleoplasm (more)
    Molecular Function RNA polymerase II transcription factor activity, sequence-specific DNA binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR011598 (1)
  • InterPro:IPR021802 (1)
  • InterPro:IPR030532 (1)
  • InterPro:IPR031867 (1)
    		•
  • PROSITE:PS50888 (1)
    		•
  • Pfam:PF00010 (1)
  • Pfam:PF11851 (1)
  • Pfam:PF15951 (1)
    		•
    TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM mitfb No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    mitfbEncodes: [EST] eu230 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131847 (1) 1595bp
    Select Tool
    Genomic GenBank:CABZ01052956 (1) 16897bp
    Select Tool
    Polypeptide UniProtKB:F1Q885 (1) 500aa
    Select Tool
    Sequence Clusters UniGene:83675 (1)
    Sequence Information (all 15)
    OTHER mitfb GENE PAGES
  • Gene:114833 (1)
  • Ensembl(GRCz10):ENSDARG00000037833 (1)
    • ORTHOLOGY for mitfb (Chr: 23)
    CITATIONS (23)