ZFIN ID: ZDB-GENE-010817-1
Gene Name: angiopoietin 1
Gene Symbol: angpt1
Previous Names: ang1 (1), wu:fc76g06
Location: Chr: 19 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 9 figures from 8 publications
Wild-type Stages, Structures: Gastrula:Shield (6.0h-8.0h) to Juvenile:Days 30-44 (30d-45d, 10 mm, adult fins/pigment)
  brain, caudal periventricular hypothalamus, dorsal periventricular hypothalamus, forebrain (all 15) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
la028073Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14264 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-angpt1 (1), MO2-angpt1 (1), MO3-angpt1 (1)
    PHENOTYPE
    Data: 3 figures from 3 publications
    Observed in: blood circulation, blood vessel morphogenesis, brain, common cardinal vein (all 7) expand
    DISEASE ASSOCIATED WITH angpt1 HUMAN ORTHOLOG No data available
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process blood vessel development (more)
    Molecular Function receptor tyrosine kinase binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002181 (1)
  • InterPro:IPR014715 (1)
  • InterPro:IPR014716 (1)
  • InterPro:IPR020837 (1)
  • InterPro:IPR028843 (1)
  • PROSITE:PS00514 (1)
  • PROSITE:PS51406 (1)
  • Pfam:PF00147 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA angpt1-001 (1) 2164
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM angpt1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    angpt1Contained in: [BAC] CH73-338A11 (1) (order this), CH211-121H11 (1) (order this), DKEY-163O15 (1) (order this)
    angpt1Encodes: [EST] fc76g06 (1)
    [cDNA] MGC:195033 (1) (order this), MGC:195051 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131813 (1) 1595bp
    Genomic GenBank:AL953858 (1) 145746bp
    Select Tool
    Polypeptide UniProtKB:B3DJK2 (1) 513aa
    Sequence Clusters UniGene:12619 (1)
    Sequence Information (all 23)
    OTHER angpt1 GENE PAGES 
  • Gene:114407 (1)
  • VEGA:OTTDARG00000015655 (1)
  • Ensembl(GRCz10):ENSDARG00000030364 (1)
  • ORTHOLOGY for angpt1 (Chr: 19) 
    Species Symbol Chromosome Accession # Evidence
    Human ANGPT1 8
  • Gene:284
  • OMIM:601667
  • HGNC:484
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Angpt1 15
  • MGI:108448
  • Gene:11600
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (39)