ZFIN ID: ZDB-GENE-010817-1
Gene Name: angiopoietin 1
Gene Symbol: angpt1
Previous Names: ang1 (1), wu:fc76g06
Location: Chr: 19   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 8 figures from 7 publications
Wild-type Stages, Structures: Gastrula:Shield (6.0h-8.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  forebrain, heart tube, hypochord, midbrain (all 7) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Mutagen Suppliers
la028073Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14264 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-angpt1 (1), MO2-angpt1 (1)
    PHENOTYPE
    Data: Fig. 4 from Lamont et al., 2010
    Observed in: blood circulation, heart, heart morphogenesis
    DISEASE ASSOCIATED WITH angpt1 HUMAN ORTHOLOG No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process blood vessel development (more)
    Molecular Function receptor tyrosine kinase binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002181 (1)
  • InterPro:IPR014715 (1)
  • InterPro:IPR014716 (1)
  • InterPro:IPR020837 (1)
  • InterPro:IPR028843 (1)
  • PROSITE:PS00514 (1)
  • PROSITE:PS51406 (1)
  • Pfam:PF00147 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA angpt1-001 (1) 2164
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM angpt1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    angpt1 Contained in: [BAC] CH73-338A11 (1) (order this), CH211-121H11 (1) (order this), DKEY-163O15 (1) (order this)
    angpt1 Encodes: [EST] fc76g06 (1)
    [cDNA] MGC:195033 (1) (order this), MGC:195051 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131813 (1) 1595 bp
    Genomic GenBank:AL953858 (1) 145746 bp
    Select Tool
    Polypeptide UniProtKB:B3DJK2 (1) 513 aa
    Sequence Clusters UniGene:12619 (1)
    Sequence Information (all 23)
    OTHER angpt1 GENE PAGES
  • Gene:114407 (1)
  • VEGA:OTTDARG00000015655 (1)
  • Ensembl(Zv9):ENSDARG00000030364 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish angpt1 19  
    Human ANGPT1 8 (8q23.1)
  • OMIM:601667
  • Gene:284
  • Mouse Angpt1 15 ( 16.69 cM)
  • MGI:108448
  • Gene:11600
  • Orthology Details
    CITATIONS (35)