Gene

angpt1

ID
ZDB-GENE-010817-1
Name
angiopoietin 1
Symbol
angpt1 Nomenclature History
Previous Names
  • ang1 (1)
  • wu:fc76g06
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have receptor tyrosine kinase binding activity. Involved in blood vessel development and brain development. Human ortholog(s) of this gene implicated in brain ischemia; diabetic retinopathy; and hypertension. Is expressed in several structures, including brain; heart tube; hypochord; medial longitudinal fasciculus; and ventral mesenchyme. Orthologous to human ANGPT1 (angiopoietin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
16 figures from 14 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With angpt1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Angioedema, hereditary, 5 619361
Associated With angpt1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020837 Fibrinogen, conserved site
Domain IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
Family IPR028843 Angiopoietin-1
Homologous_superfamily IPR014716 Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1
Homologous_superfamily IPR036056 Fibrinogen-like, C-terminal
Domain Details Per Protein
Protein Length Angiopoietin-1 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 Fibrinogen, conserved site Fibrinogen-like, C-terminal
UniProtKB:Q90Z19 513
UniProtKB:B3DJK2 513
UniProtKB:Q1MT43 513
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations