ZFIN ID: ZDB-GENE-010724-8
Gene Name: discs, large homolog 1 (Drosophila)
Gene Symbol: dlg1    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: SAP-97A (1), wu:fc34d02

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have phosphatase binding activity and protein kinase binding activity. Predicted to be involved in several processes, including actin cytoskeleton organization; endothelial cell proliferation; and protein localization to membrane. Predicted to colocalize with ionotropic glutamate receptor complex. Is expressed in nervous system; neural crest; neural tube; pigment cell; and trigeminal placode. Human ortholog(s) of this gene implicated in invasive ductal carcinoma. Orthologous to human DLG1 (discs large MAGUK scaffold protein 1).
Genome Resources: Alliance (1),  Gene:114446 (1),  Ensembl(GRCz11):ENSDARG00000009677 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la011233Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la025485Tg Transgenic Insertion Unknown Unknown DNA
    mn0972Gt Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14850 Point Mutation Unknown Premature Stop ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dlg1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dlg1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actin filament organization (more)
    Cellular Component basolateral plasma membrane (more)
    Molecular Function phosphatase binding (more)
    GO Terms (all 23)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dlg1-201 (1)    Ensembl 5039
    ncRNA dlg1-003 (1)    Ensembl 704
    dlg1-005 (1)    Ensembl 468
    dlg1-006 (1)    Ensembl 669
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dlg1 No data available
    MARKER RELATIONSHIPS
    dlg1 Contained in: [BAC] CH73-317L11 (1), CH211-157O9 (1), CH211-160M12 (1), CH211-241M14 (1)
    [Fosmid] CH1073-194H11 (1)
    dlg1 Encodes: [EST] fc34d02 (1)
    [cDNA] MGC:55810 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199526 (1) 2917 nt
    Genomic GenBank:BX255895 (1) 159627 nt
    Select Tool
    Polypeptide UniProtKB:E7FAT1 (1) 909 aa
    Sequence Information (all 69)
    ORTHOLOGY for dlg1 ( Chr: 6 )
    CITATIONS (34)