ZFIN ID: ZDB-GENE-010724-5
Gene Name: ADP-ribosylation factor 1
Gene Symbol: arf1    Nomenclature History

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Previous Names: wu:fb33e02, wu:fb78h01

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have GTP binding activity. Involved in semicircular canal development. Predicted to localize to cytoplasm and plasma membrane. Is expressed in brain; head; pharyngeal arch 3-7; and semicircular canal. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human ARF1 (ADP ribosylation factor 1).
Genome Resources: Alliance (1),  Gene:114428 (1),  Ensembl(GRCz11):ENSDARG00000009484 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55900]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-arf1 N/A 1
MO2-arf1 N/A 1
DISEASE ASSOCIATED WITH arf1 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Periventricular nodular heterotopia 8 618185
DISEASE ASSOCIATED WITH arf1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process semicircular canal development (more)
Cellular Component cytoplasm (more)
Molecular Function GTP binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
CONSTRUCTS WITH SEQUENCES FROM arf1 No data available
MARKER RELATIONSHIPS
arf1 Encodes: [EST] fb33e02, fb78h01 (1)
[cDNA] MGC:55900 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_201452 (1) 2045 nt
Genomic GenBank:CABZ01075147 (1) 23737 nt
Polypeptide UniProtKB:Q803D1 (1) 180 aa
Sequence Information (all 15)
ORTHOLOGY for arf1 ( Chr: 2 )
CITATIONS (22)