Gene
dnase2
- ID
- ZDB-GENE-010724-16
- Name
- deoxyribonuclease II, lysosomal
- Symbol
- dnase2 Nomenclature History
- Previous Names
-
- fa56d08
- fa92d01
- wu:fa56d08
- wu:fa92d01
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have deoxyribonuclease II activity. Predicted to be involved in apoptotic DNA fragmentation. Orthologous to human DNASE2 (deoxyribonuclease 2, lysosomal).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Zhang et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Matsui et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Autoinflammatory-pancytopenia syndrome | 619858 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR004947 | Deoxyribonuclease II |
Domain Details Per Protein
| Protein | Length | Deoxyribonuclease II |
|---|---|---|
|
UniProtKB:B0JZP5
|
367 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
dnase2-201
(1)
|
Havana | 3476 nt |
Interactions and Pathways
No data available
Plasmids
No data available