ZFIN ID: ZDB-GENE-010724-10
Gene Name: eph receptor A3
Gene Symbol: epha3    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have transmembrane-ephrin receptor activity. Involved in mesoderm migration involved in gastrulation and somitogenesis. Predicted to localize to integral component of plasma membrane; neuron projection; and receptor complex. Is expressed in optic cup. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human EPHA3 (EPH receptor A3).
Genome Resources: Alliance (1),  Gene:795902 (1),  Ensembl(GRCz11):ENSDARG00000039373 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Gastrula:Shield (6.0h-8.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa18943 Point Mutation Unknown Splice Site ENU
sa25420 Point Mutation Unknown Premature Stop ENU
sa38730 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41384 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH epha3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH epha3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process mesoderm migration involved in gastrulation (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 22)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM epha3 No data available
    MARKER RELATIONSHIPS
    epha3 Contained in: [BAC] DKEY-114E9 (order this)
    [Fosmid] CH1073-431E9
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001365172 (1)
    Genomic GenBank:CR589884 (1) 151480 nt
    Select Tool
    Polypeptide UniProtKB:F1Q9D9 (1) 963 aa
    Sequence Information (all 20)
    ORTHOLOGY for epha3 ( Chr: 9 )
    CITATIONS (21)