Gene

efnb1

ID
ZDB-GENE-010618-2
Name
ephrin-B1
Symbol
efnb1 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have ephrin receptor binding activity. Involved in embryonic liver development and optic vesicle morphogenesis. Predicted to localize to plasma membrane. Is expressed in several structures, including alar plate midbrain region; central nervous system; hepatoblast; intestinal rod; and liver and biliary system. Human ortholog(s) of this gene implicated in craniofrontonasal syndrome and dysostosis. Orthologous to human EFNB1 (ephrin B1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With efnb1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
craniofrontonasal syndrome Alliance Craniofrontonasal dysplasia 304110
Associated With efnb1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019765 Ephrin, conserved site
Domain IPR001799 Ephrin receptor-binding domain
Family IPR031328 Ephrin
Homologous_superfamily IPR008972 Cupredoxin
Domain Details Per Protein
Protein Length Cupredoxin Ephrin Ephrin, conserved site Ephrin receptor-binding domain
UniProtKB:B0CM03 369
UniProtKB:Q90Z33 341
UniProtKB:A0A2R8Q1M3 369
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations