ZFIN ID: ZDB-GENE-010501-5
Gene Name: BCL2 associated athanogene 6
Gene Symbol: bag6    Nomenclature History

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Previous Names: bat3, etID62210.15 (1), wu:fi30e10 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have misfolded protein binding activity and polyubiquitin modification-dependent protein binding activity. Predicted to be involved in ubiquitin-dependent ERAD pathway. Predicted to localize to BAT3 complex. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and osteoarthritis. Orthologous to human BAG6 (BAG cochaperone 6).
Genome Resources: Alliance (1),  Gene:83910 (1),  Ensembl(GRCz11):ENSDARG00000075892 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55412]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la019358Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14864 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa28504 Point Mutation Unknown Splice Site ENU
    sa32052 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35957 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45549 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH bag6 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH bag6 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ubiquitin-dependent ERAD pathway (more)
    Cellular Component BAT3 complex (more)
    Molecular Function misfolded protein binding (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    Browsers: NCBI
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM bag6 No data available
    MARKER RELATIONSHIPS
    bag6 Contained in: [BAC] DKEY-48O24 (1) (order this)
    bag6 Encodes: [EST] fi30e10
    [cDNA] MGC:55412 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201288 (1) 4479 nt
    Genomic GenBank:BX530057 178280 nt
    Select Tool
    Polypeptide UniProtKB:F1QIQ2 (1) 1209 aa
    Sequence Information (all 15)
    ORTHOLOGY for bag6 ( Chr: 15 )
    CITATIONS (27)