ZFIN is now using GRCz12tu for Genomic Data
Gene
pbrm1l
- ID
- ZDB-GENE-010501-3
- Name
- polybromo 1, like
- Symbol
- pbrm1l Nomenclature History
- Previous Names
-
- pb1 (1)
- zgc:100857
- zgc:113882
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable chromatin binding activity. Predicted to be involved in chromatin remodeling and transcription elongation by RNA polymerase II. Predicted to act upstream of or within chromatin organization. Predicted to be located in nucleus. Predicted to be part of RSC-type complex and SWI/SNF complex. Human ortholog(s) of this gene implicated in extrahepatic bile duct adenocarcinoma; lung non-small cell carcinoma; lung small cell carcinoma; and renal cell carcinoma. Orthologous to human PBRM1 (polybromo 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu469 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018359 | Bromodomain, conserved site |
| Domain | IPR001025 | Bromo adjacent homology (BAH) domain |
| Domain | IPR001487 | Bromodomain |
| Domain | IPR009071 | High mobility group box domain |
| Domain | IPR037968 | Protein polybromo-1, Bromodomain 5 |
| Family | IPR037382 | Remodelling complex subunit Rsc/polybromo |
| Homologous_superfamily | IPR036427 | Bromodomain-like superfamily |
| Homologous_superfamily | IPR036910 | High mobility group box domain superfamily |
| Homologous_superfamily | IPR043151 | Bromo adjacent homology (BAH) domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Bromo adjacent homology (BAH) domain | Bromo adjacent homology (BAH) domain superfamily | Bromodomain | Bromodomain, conserved site | Bromodomain-like superfamily | High mobility group box domain | High mobility group box domain superfamily | Protein polybromo-1, Bromodomain 5 | Remodelling complex subunit Rsc/polybromo |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:E7EZ71 | InterPro | 1587 | |||||||||
| UniProtKB:A0A8M2BG23 | InterPro | 1657 | |||||||||
| UniProtKB:A0AB32TT87 | InterPro | 1629 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pbrm1l-201
(1)
|
Ensembl | 5,481 nt | ||
| mRNA |
pbrm1l-202
(1)
|
Ensembl | 5,449 nt | ||
| mRNA |
pbrm1l-203
(1)
|
Ensembl | 5,611 nt | ||
| mRNA |
pbrm1l-206
(1)
|
Ensembl | 1,475 nt | ||
| ncRNA |
pbrm1l-003
(1)
|
Ensembl | 767 nt | ||
| ncRNA |
pbrm1l-005
(1)
|
Ensembl | 754 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers