Gene
cry3b
- ID
- ZDB-GENE-010426-5
- Name
- cryptochrome circadian regulator 3b
- Symbol
- cry3b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable DNA binding activity and FAD binding activity. Acts upstream of or within negative regulation of DNA-templated transcription. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including brain; endocrine system; eye; intestine; and liver and biliary system. Human ortholog(s) of this gene implicated in delayed sleep phase syndrome. Orthologous to human CRY1 (cryptochrome circadian regulator 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Delayed sleep phase disorder, susceptibility to} | 614163 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR005101 | Cryptochrome/DNA photolyase, FAD-binding domain |
| Domain | IPR006050 | DNA photolyase, N-terminal |
| Family | IPR002081 | Cryptochrome/DNA photolyase class 1 |
| Homologous_superfamily | IPR014729 | Rossmann-like alpha/beta/alpha sandwich fold |
| Homologous_superfamily | IPR036134 | Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily |
| Homologous_superfamily | IPR036155 | Cryptochrome/photolyase, N-terminal domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Cryptochrome/DNA photolyase class 1 | Cryptochrome/DNA photolyase, FAD-binding domain | Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily | Cryptochrome/photolyase, N-terminal domain superfamily | DNA photolyase, N-terminal | Rossmann-like alpha/beta/alpha sandwich fold |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AXA7 | InterPro | 640 | ||||||
| UniProtKB:A0A8M1PCZ5 | InterPro | 639 | ||||||
| UniProtKB:A0A8M9P4C5 | InterPro | 639 | ||||||
| UniProtKB:A0AB32TG61 | InterPro | 638 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cry1bb-202
(1)
|
Ensembl | 2,550 nt | ||
| mRNA |
cry3b-201
(1)
|
Ensembl | 3,057 nt | ||
| mRNA |
cry3b-205
(1)
|
Ensembl | 1,917 nt | ||
| mRNA |
cry3b-206
(1)
|
Ensembl | 1,920 nt | ||
| mRNA |
cry3b-207
(1)
|
Ensembl | 3,377 nt | ||
| mRNA |
cry3b-208
(1)
|
Ensembl | 3,460 nt | ||
| ncRNA |
cry1bb-002
(1)
|
Ensembl | 1,068 nt | ||
| ncRNA |
cry1bb-003
(1)
|
Ensembl | 922 nt |
Interactions and Pathways
No data available
Plasmids
No data available