Gene

cry3a

ID
ZDB-GENE-010426-4
Name
cryptochrome circadian regulator 3a
Symbol
cry3a Nomenclature History
Previous Names
  • cry1ba
  • cry2a
  • cry3a (1)
  • zcry2a (1)
  • zgc:110521
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have DNA binding activity and FAD binding activity. Involved in negative regulation of transcription, DNA-templated; response to light stimulus; and response to temperature stimulus. Predicted to localize to cytoplasm and nucleus. Is expressed in several structures, including brain; eye; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome. Orthologous to human CRY1 (cryptochrome circadian regulator 1).
Genome Resources
Note
None
Expression
All Expression Data
16 figures from 12 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cry3a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Delayed sleep phase disorder, susceptibility to} 614163
Associated With cry3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain
Domain IPR006050 DNA photolyase, N-terminal
Homologous_superfamily IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
Homologous_superfamily IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily
Homologous_superfamily IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily
Domain Details Per Protein
Protein Length Cryptochrome/DNA photolyase, FAD-binding domain Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Cryptochrome/photolyase, N-terminal domain superfamily DNA photolyase, N-terminal Rossmann-like alpha/beta/alpha sandwich fold
UniProtKB:A0A2R8Q807 570
UniProtKB:A0A2R8QN27 553
UniProtKB:A0A2R8QCA4 563
UniProtKB:Q9I915 655
UniProtKB:Q503J5 658
UniProtKB:B0S7X5 659
UniProtKB:A0A2R8QLY8 539
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations