Gene
cry3a
- ID
- ZDB-GENE-010426-4
- Name
- cryptochrome circadian regulator 3a
- Symbol
- cry3a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have DNA binding activity and FAD binding activity. Involved in negative regulation of transcription, DNA-templated; response to light stimulus; and response to temperature stimulus. Predicted to localize to cytoplasm and nucleus. Is expressed in several structures, including brain; eye; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome. Orthologous to human CRY1 (cryptochrome circadian regulator 1).
- Genome Resources
- Note
- None
- All Expression Data
- 16 figures from 12 publications
- Cross-Species Comparison
- High Throughput Data
- No data available
- Thisse Expression Data
-
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
{Delayed sleep phase disorder, susceptibility to} | 614163 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR005101 | Cryptochrome/DNA photolyase, FAD-binding domain |
Domain | IPR006050 | DNA photolyase, N-terminal |
Homologous_superfamily | IPR014729 | Rossmann-like alpha/beta/alpha sandwich fold |
Homologous_superfamily | IPR036134 | Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily |
Homologous_superfamily | IPR036155 | Cryptochrome/photolyase, N-terminal domain superfamily |
Domain Details Per Protein
Protein | Length | Cryptochrome/DNA photolyase, FAD-binding domain | Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily | Cryptochrome/photolyase, N-terminal domain superfamily | DNA photolyase, N-terminal | Rossmann-like alpha/beta/alpha sandwich fold |
---|---|---|---|---|---|---|
UniProtKB:A0A2R8Q807
|
570 | |||||
UniProtKB:A0A2R8QN27
|
553 | |||||
UniProtKB:A0A2R8QCA4
|
563 | |||||
UniProtKB:Q9I915
|
655 | |||||
UniProtKB:Q503J5
|
658 | |||||
UniProtKB:B0S7X5
|
659 | |||||
UniProtKB:A0A2R8QLY8
|
539 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
cry1ba-201
(1)
|
2388 nt | |
mRNA |
cry1ba-202
(1)
|
4510 nt | |
ncRNA |
cry1ba-003
(1)
|
698 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Gene Tree
- Ensembl