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General Information
ZIRC
ZFIN ID: ZDB-GENE-010404-1
Gene Name: NK2 homeobox 1
Gene Symbol: nkx2.1
Sequence Ontology ID : SO:0001217

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Previous Names: nk2.1b, nkx2.1b, nkx2.4b (1), titf1b (1), wu:fc31g10

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(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in hypothalamus development. Predicted to localize  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
PHENOTYPE No data available
DISEASE ASSOCIATED WITH nkx2.1 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
choreatic disease Chorea, hereditary benign 118700
thyroid gland papillary carcinoma {Thyroid cancer, nonmedullary, 1} 188550
Choreoathetosis, hypothyroidism, and neonatal respiratory distress 610978
DISEASE ASSOCIATED WITH nkx2.1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process hypothalamus development (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 11)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA nkx2.1-201 (1) 1808
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM nkx2.1 No data available
MARKER RELATIONSHIPS
nkx2.1 Contained in: [BAC] DKEY-34N18 (1) (order this)
nkx2.1 Encodes: [EST] fc31g10
[cDNA] MGC:194040 (1) (order this), MGC:194045 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_131776 (1) 1773 bp
Genomic GenBank:BX511145 (1) 102544 bp
Select Tool
Polypeptide UniProtKB:B3DH68 (1) 346 aa
Sequence Clusters UniGene:78792 (1)
Sequence Information (all 17)
ORTHOLOGY for nkx2.1 ( Chr: 17 )
CITATIONS (55)