ZFIN ID: ZDB-GENE-010328-19
Gene Name: eukaryotic translation initiation factor 4h
Gene Symbol: eif4h    Nomenclature History

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Previous Names: wbscr1, zgc:77282 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have RNA binding activity and ribosomal small subunit binding activity. Predicted to be involved in eukaryotic translation initiation factor 4F complex assembly and formation of translation preinitiation complex. Predicted to localize to the polysome. Human ortholog(s) of this gene implicated in Williams-Beuren syndrome. Orthologous to human EIF4H (eukaryotic translation initiation factor 4H).
Genome Resources: Alliance (1),  Gene:402996 (1),  Ensembl(GRCz11):ENSDARG00000042252 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:77282]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7163471]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa19101 Point Mutation Unknown Splice Site ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH eif4h HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH eif4h VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process translation (more)
Cellular Component polysome (more)
Molecular Function nucleic acid binding (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Domain IPR034229 eIF4H, RNA recognition motif
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily IPR035979 RNA-binding domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA eif4h-201 (1)    Ensembl 877
eif4h-202 (1)    Ensembl 2440
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM eif4h No data available
MARKER RELATIONSHIPS
eif4h Contained in: [BAC] CH73-63K18 (1)
eif4h Encodes: [EST] IMAGE:7163471 (1)
[cDNA] MGC:77282 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_205695 (1) 1339 nt
Genomic GenBank:CT962513 (1) 76395 nt
Select Tool
Polypeptide UniProtKB:Q6P0F5 (1) 263 aa
Sequence Information (all 24)
ORTHOLOGY for eif4h ( Chr: 15 )
CITATIONS (26)