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ZIRC
ZFIN ID: ZDB-GENE-010320-2
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Gene Name: cyclin-dependent kinase 7
Gene Symbol: cdk7    Nomenclature History

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Previous Name: zgc:85821

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II and protein phosphorylation. Predicted to localize to the cytoplasm and transcription factor TFIIK complex. Is expressed in several structures, including heart; integument; liver; nervous system; and pleuroperitoneal region. Orthologous to human CDK7 (cyclin dependent kinase 7).
Genome Resources: Alliance (1),  Gene:405897 (1),  Ensembl(GRCz11):ENSDARG00000051916 (2)
GENE EXPRESSION
All Expression Data: 6 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:85821]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-cdk7 N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH cdk7 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH cdk7 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process phosphorylation (more)
Cellular Component transcription factor TFIIH holo complex (more)
Molecular Function ATP binding (more)
GO Terms (all 15)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR008271 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR017441 (1)
  • InterPro:IPR037770 (1)
  • PROSITE:PS00107 (1)
  • PROSITE:PS00108 (1)
  • PROSITE:PS50011 (1)
  • Pfam:PF00069 (1)
    • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cdk7-201 (1)    Ensembl 1311
    Select Tool
    cdk7-203 (1)    Ensembl 829
    Select Tool
    Browsers: UCSC,  NCBI,  Ensembl,  ZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cdk7 No data available
    MARKER RELATIONSHIPS
    cdk7 Contained in: [BAC] CH211-198E13 (1) (order this)
    cdk7 Encodes: [cDNA] MGC:85821 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212961 (1) 1260 bp
    Select Tool
    Genomic GenBank:AL935198 (1) 200697 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q2V6H0 (1) 345 aa
    Select Tool
    Sequence Clusters UniGene:3533 (1)
    Sequence Information (all 19)
    ORTHOLOGY for cdk7 ( Chr: 5 )
    CITATIONS (25)