Gene

cdk7

ID
ZDB-GENE-010320-2
Name
cyclin-dependent kinase 7
Symbol
cdk7 Nomenclature History
Previous Names
  • zgc:85821
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in phosphorylation of RNA polymerase II C-terminal domain and positive regulation of transcription by RNA polymerase II. Predicted to localize to cytoplasm and transcription factor TFIIK complex. Is expressed in several structures, including heart; integument; liver; nervous system; and pleuroperitoneal region. Orthologous to human CDK7 (cyclin dependent kinase 7).
Genome Resources
Note
None
Expression
All Expression Data
6 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cdk7 Human Ortholog
No data available
Associated With cdk7 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Family IPR037770 Cyclin-dependent kinase 7
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Cyclin-dependent kinase 7 Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:A4VAK7 173
UniProtKB:Q2V6H0 345
UniProtKB:A0A0R4IXP6 254
UniProtKB:Q6NWC5 311
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations