Gene
cdk7
- ID
- ZDB-GENE-010320-2
- Name
- cyclin-dependent kinase 7
- Symbol
- cdk7 Nomenclature History
- Previous Names
-
- zgc:85821
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in phosphorylation of RNA polymerase II C-terminal domain and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within phosphorylation. Predicted to be part of transcription factor TFIIK complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including heart; integument; liver; nervous system; and pleuroperitoneal region. Orthologous to human CDK7 (cyclin dependent kinase 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
-
- GEO (1) Expression Atlas (1) UCSC scRNA-seq (1)
- Thisse Expression Data
-
- MGC:85821 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cyclin-dependent kinase 7 | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|
|
UniProtKB:A4VAK7
|
173 | |||||
|
UniProtKB:Q2V6H0
|
345 | |||||
|
UniProtKB:A0A0R4IXP6
|
254 | |||||
|
UniProtKB:Q6NWC5
|
311 |
Interactions and Pathways
No data available
Plasmids
No data available