Gene
cdk1
- ID
- ZDB-GENE-010320-1
- Name
- cyclin dependent kinase 1
- Symbol
- cdk1 Nomenclature History
- Previous Names
-
- cdc2
- wu:fc30e01
- zgc:92032
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Is predicted to enable RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin-dependent protein serine/threonine kinase activity. Involved in G2/M transition of mitotic cell cycle; mitotic G2 DNA damage checkpoint signaling; and protein phosphorylation. Acts upstream of or within regulation of mitotic cell cycle, embryonic. Is expressed in eye. Human ortholog(s) of this gene implicated in breast cancer; cervical cancer; and urinary bladder cancer. Orthologous to human CDK1 (cyclin dependent kinase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 17 figures from 14 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|
|
UniProtKB:Q7T3L7
|
302 |
Interactions and Pathways
No data available
Plasmids
No data available