ZFIN ID: ZDB-GENE-010110-2
Gene Name: TAP binding protein (tapasin), tandem duplicate 1
Gene Symbol: tapbp.1
Sequence Ontology ID : SO:0000704

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Previous Names: tapbp (1), tpsn, zgc:109814

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(Including Attributions)
Location: Chr: 19 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to be involved in antigen processing and presentation of endogenous peptide antigen via MHC class I; predicted to localize to the membrane; orthologous to human TAPBP (TAP binding protein).
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (10 images) from Thisse et al., 2004 [MGC:109814]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Pharyngula:Prim-25 (36.0h-42.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la020938Tg Transgenic Insertion Unknown Unknown DNA
sa36774 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tapbp.1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    MHC class I deficiency Bare lymphocyte syndrome, type I 604571
    DISEASE ASSOCIATED WITH tapbp.1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process antigen processing and presentation of endogenous peptide antigen via MHC class I (more)
    Cellular Component membrane (more)
    Molecular Function molecular_function (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003599 (1)
  • InterPro:IPR007110 (1)
  • InterPro:IPR008056 (1)
  • InterPro:IPR013106 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR036179 (1)
  • PROSITE:PS50835 (1)
  • Pfam:PF07686 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tapbp.1-001 (1) 1737
    tapbp.1-201 (1) 1715
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tapbp.1 No data available
    MARKER RELATIONSHIPS
    tapbp.1Contained in: [BAC] CH73-213J4 (1) (order this), DKEY-264N13 (1) (order this)
    [PAC] BUSM1-179B20 (1) (order this)
    tapbp.1Encodes: [cDNA] cssl:d105 (1), MGC:109814 (1) (order this), MGC:171979 (1) (order this), MGC:192901 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA GenBank:BC152022 (1) 1702bp
    Genomic GenBank:BX927188 163213bp
    Select Tool
    Polypeptide UniProtKB:A7MC30 (1) 443aa
    Sequence Information (all 18)
    OTHER tapbp.1 GENE PAGES
  • Alliance (1)
  • VEGA:OTTDARG00000001714 (1)
  • VEGA:OTTDARG00000031769 (1)
  • Ensembl(GRCz11):ENSDARG00000079402 (2)
  • ORTHOLOGY for tapbp.1 (Chr: 19)
    CITATIONS (35)