ZFIN ID: ZDB-GENE-010108-1
Gene Name: ventral homeobox
Gene Symbol: vox    Nomenclature History

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Previous Names: vega1, zgc:136532

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Exhibits protein heterodimerization activity and protein homodimerization activity. Involved in dorsal/ventral pattern formation; regulation of endodermal cell fate specification; and regulation of mesodermal cell fate specification. Predicted to localize to nucleus. Is expressed in several structures, including cloacal chamber; embryonic structure; epidermis; hindbrain neural plate; and midbrain neural keel. Orthologous to human VENTX (VENT homeobox).
Genome Resources: Alliance (1),  Gene:64807 (1),  Ensembl(GRCz11):ENSDARG00000099761 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la018734Tg Transgenic Insertion Unknown Unknown DNA
la018735Tg Transgenic Insertion Unknown Unknown DNA
sa11047 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • st9 Point Mutation Unknown Missense ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-vox N/A 7
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH vox HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH vox VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dorsal/ventral pattern formation (more)
    Cellular Component nucleus (more)
    Molecular Function protein heterodimerization activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM vox No data available
    MARKER RELATIONSHIPS
    vox Encodes: [EST] eu503 (1)
    [cDNA] MGC:136532 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131698 (1)
    Genomic GenBank:DU644532 (1) 344 nt
    Polypeptide UniProtKB:Q568V6 (1) 265 aa
    Sequence Information (all 21)
    ORTHOLOGY for vox ( Chr: 13 )
    CITATIONS (108)