Gene

dcn

ID
ZDB-GENE-010102-1
Name
decorin
Symbol
dcn Nomenclature History
Previous Names
  • DC (1)
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to enable collagen binding activity. Predicted to be an extracellular matrix structural constituent conferring compression resistance. Acts upstream of or within cartilage development; chondroitin sulfate proteoglycan metabolic process; and convergent extension involved in axis elongation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including cranial cartilage; epidermis; nervous system; pericardial region; and periderm. Human ortholog(s) of this gene implicated in breast carcinoma; congenital stromal corneal dystrophy; and high grade glioma. Orthologous to human DCN (decorin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Zoeller et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dcn Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital stromal corneal dystrophy Alliance Corneal dystrophy, congenital stromal 610048
Associated With dcn Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000372 Leucine-rich repeat N-terminal domain
Family IPR016352 Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan
Family IPR028549 Decorin
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
Repeat IPR001611 Leucine-rich repeat
Repeat IPR003591 Leucine-rich repeat, typical subtype
Domain Details Per Protein
Protein Length Decorin Leucine-rich repeat Leucine-rich repeat domain superfamily Leucine-rich repeat N-terminal domain Leucine-rich repeat, typical subtype Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan
UniProtKB:Q9DE01 224
UniProtKB:Q803T1 373
UniProtKB:Q5RI45 373
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations