ZFIN ID: ZDB-GENE-001229-2
Gene Name: aminolevulinate, delta-, synthase 1
Gene Symbol: alas1
Sequence Ontology ID : SO:0000704

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Previous Names: ALAS-N, wu:fb58d01, wu:fi12g09, wu:fq33a02

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(Including Attributions)
Location: Chr: 11 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 7 figures (11 images) from Thisse et al., 2004 [MGC:63935]
  4 figures (16 images) from Rauch et al., 2003 [fq33a02]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  EVL, gut, liver, otic vesicle (all 10) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa21822 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH alas1 HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process biosynthetic process (more)
    Cellular Component mitochondrial matrix (more)
    Molecular Function 5-aminolevulinate synthase activity (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001917 (1)
  • InterPro:IPR004839 (1)
  • InterPro:IPR010961 (1)
  • InterPro:IPR015118 (1)
  • InterPro:IPR015421 (1)
  • InterPro:IPR015422 (1)
  • InterPro:IPR015424 (1)
  • PROSITE:PS00599 (1)
  • Pfam:PF00155 (1)
  • Pfam:PF09029 (1)
  • EC:2.3.1.37 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA alas1-001 (1) 2030
    alas1-002 (1) 739
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM alas1 No data available
    MARKER RELATIONSHIPS
    alas1Contains: [SNP] rs3728336 (1), rs3728337 (1), rs3728338 (1)
    alas1Encodes: [EST] fb58d01 (1), fi12g09 (1), fq33a02 (1) (order this)
    [cDNA] MGC:63935 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_201287 (1) 2186bp
    Polypeptide UniProtKB:F1RB22 (1) 621aa
    Sequence Clusters UniGene:4829 (1)
    Sequence Information (all 17)
    OTHER alas1 GENE PAGES
  • Alliance (1)
  • Gene:64608 (1)
  • VEGA:OTTDARG00000043200 (1)
  • Ensembl(GRCz10):ENSDARG00000021059 (1)
  • ORTHOLOGY for alas1 (Chr: 11)
    CITATIONS (24)