ZFIN ID: ZDB-GENE-001229-2
Gene Name: aminolevulinate, delta-, synthase 1
Gene Symbol: alas1
Previous Names: ALAS-N, wu:fb58d01, wu:fi12g09
Location: Chr: 11   Details
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 7 figures (11 images) from Thisse et al., 2004 [MGC:63935]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  EVL, gut, liver, otic vesicle (all 9) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH alas1 HUMAN ORTHOLOG No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process biosynthetic process (more)
Cellular Component mitochondrial matrix (more)
Molecular Function 5-aminolevulinate synthase activity (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001917 (1)
  • InterPro:IPR004839 (1)
  • InterPro:IPR010961 (1)
  • InterPro:IPR015118 (1)
  • InterPro:IPR015421 (1)
  • InterPro:IPR015422 (1)
  • InterPro:IPR015424 (1)
  • PROSITE:PS00599 (1)
  • Pfam:PF00155 (1)
  • Pfam:PF09029 (1)
  • EC:2.3.1.37 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM alas1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    alas1 Contains: [SNP] rs3728336 (1), rs3728337 (1), rs3728338 (1)
    alas1 Encodes: [EST] fb58d01 (1), fi12g09 (1)
    [cDNA] MGC:63935 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_201287 (1) 2186 bp
    Genomic GenBank:CABZ01061928 (1) 9997 bp
    Polypeptide UniProtKB:F1RB22 (1) 613 aa
    Sequence Clusters UniGene:4829 (1)
    Sequence Information (all 16)
    OTHER alas1 GENE PAGES
  • Gene:64608 (1)
  • Ensembl(Zv9):ENSDARG00000021059 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish alas1 11  
    Human ALAS1 3 (3p21.1)
  • OMIM:125290
  • Gene:211
  • Orthology Details
    CITATIONS (18)