Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-001229-2
Gene Name: aminolevulinate, delta-, synthetase 1
Gene Symbol: alas1
Previous Names: ALAS-N, wu:fb58d01, wu:fi12g09
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 7 figures (11 images) from Thisse et al., 2004 [MGC:63935]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  EVL, gut, liver, otic vesicle (all 9) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS No data available
PHENOTYPE No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process biosynthetic process (more)
Cellular Component mitochondrial matrix (more)
Molecular Function 5-aminolevulinate synthase activity (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001917 (1)
  • InterPro:IPR004839 (1)
  • InterPro:IPR010961 (1)
  • InterPro:IPR015118 (1)
  • InterPro:IPR015421 (1)
  • InterPro:IPR015422 (1)
  • InterPro:IPR015424 (1)
  • PROSITE:PS00599 (1)
  • Pfam:PF00155 (1)
  • Pfam:PF09029 (1)
  • EC:2.3.1.37 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM alas1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    alas1 Contains: [SNP] rs3728336 (1), rs3728337 (1), rs3728338 (1)
    alas1 Encodes: [EST] fb58d01 (1), fi12g09 (1)
    [cDNA] MGC:63935 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_201287 (1) 2186 bp
    Genomic GenBank:CABZ01061928 (1) 9997 bp
    Polypeptide UniProtKB:F1RB22 (1) 613 aa
    Sequence Clusters UniGene:4829 (1)
    Sequence Information (all 16)
    OTHER alas1 GENE PAGES
  • Gene:64608 (1)
  • Ensembl(Zv9):ENSDARG00000021059 (1)
  • MAPPING INFORMATION
    Chr: 11 Details
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA CL
    Zebrafish alas1 11  
    Human ALAS1 3 (3p21.1)
  • OMIM:125290
  • Gene:211
  • CITATIONS (18)