ZFIN ID: ZDB-GENE-001229-2
Gene Name: aminolevulinate, delta-, synthase 1
Gene Symbol: alas1

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Previous Names: ALAS-N, wu:fb58d01, wu:fi12g09, wu:fq33a02

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(Including Attributions)
Location: Chr: 11 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 7 figures (11 images) from Thisse et al., 2004 [MGC:63935]
  4 figures (16 images) from Rauch et al., 2003 [fq33a02]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  EVL, gut, liver, otic vesicle (all 10) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa21822 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH alas1 HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process biosynthetic process (more)
    Cellular Component mitochondrial matrix (more)
    Molecular Function 5-aminolevulinate synthase activity (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001917 (1)
  • InterPro:IPR004839 (1)
  • InterPro:IPR010961 (1)
  • InterPro:IPR015118 (1)
  • InterPro:IPR015421 (1)
  • InterPro:IPR015422 (1)
  • InterPro:IPR015424 (1)
  • PROSITE:PS00599 (1)
  • Pfam:PF00155 (1)
  • Pfam:PF09029 (1)
  • EC:2.3.1.37 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA alas1-001 (1) 2030
    alas1-002 (1) 739
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM alas1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    alas1Contains: [SNP] rs3728336 (1), rs3728337 (1), rs3728338 (1)
    alas1Encodes: [EST] fb58d01 (1), fi12g09 (1), fq33a02 (1) (order this)
    [cDNA] MGC:63935 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_201287 (1) 2186bp
    Genomic GenBank:CABZ01061928 (1) 9997bp
    Polypeptide UniProtKB:F1RB22 (1) 621aa
    Sequence Clusters UniGene:4829 (1)
    Sequence Information (all 18)
    OTHER alas1 GENE PAGES
  • Gene:64608 (1)
  • VEGA:OTTDARG00000043200 (1)
  • Ensembl(GRCz10):ENSDARG00000021059 (1)
  • ORTHOLOGY for alas1 (Chr: 11)
    Species Symbol Chromosome Accession # Evidence
    Human ALAS1 3
  • Gene:211
  • OMIM:125290
  • HGNC:396
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (21)