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Gene

psmb12

ID
ZDB-GENE-001208-1
Name
proteasome 20S subunit beta 12
Symbol
psmb12 Nomenclature History
Previous Names
  • psmb11 (2)
  • beta1t (1)
  • zgc:92422
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to enable threonine-type endopeptidase activity. Predicted to be involved in proteasomal protein catabolic process. Predicted to act upstream of or within proteolysis involved in cellular protein catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of proteasome core complex, beta-subunit complex. Human ortholog(s) of this gene implicated in autoimmune disease (multiple); lymphoma; and renal cell carcinoma. Orthologous to human PSMB9 (proteasome 20S subunit beta 9).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With psmb12 Human Ortholog
No data available
Associated With psmb12 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR016050 Proteasome beta-type subunit, conserved site
Family IPR000243 Peptidase T1A, proteasome beta-subunit
Family IPR001353 Proteasome, subunit alpha/beta
Family IPR023333 Proteasome B-type subunit
Homologous_superfamily IPR029055 Nucleophile aminohydrolases, N-terminal
Domain Details Per Protein
Protein Length Nucleophile aminohydrolases, N-terminal Peptidase T1A, proteasome beta-subunit Proteasome beta-type subunit, conserved site Proteasome B-type subunit Proteasome, subunit alpha/beta
UniProtKB:Q9PUS6 217
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations