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ZIRC
ZFIN ID: ZDB-GENE-000928-1
Gene Name: ferrochelatase
Gene Symbol: fech
Sequence Ontology ID : SO:0000704

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Previous Names: fch (1), dracula, drc, frx, zgc:109851

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(Including Attributions)
Location: Chr: 21 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits ferrochelatase activity. Involved in erythrocyte maturation. Predicted to localize to the mitochondrion. Human ortholog(s) of this gene implicated in cutaneous porphyria and erythropoietic  ...
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Directly Submitted Expression Data: 6 figures (8 images) from Thisse et al., 2004 [MGC:109851]
Wild-type Stages, Structures: Segmentation:10-13 somites (14.0h-16.0h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
m87 Unknown Unknown Unknown ENU
m159 Unknown Unknown Unknown ENU
m248 Point Mutation Donor Splice Site Unknown ENU
m328 Unknown Unknown Unknown ENU
sa23835 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37199 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tu271 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH fech HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    erythropoietic protoporphyria Protoporphyria, erythropoietic, 1 177000
    DISEASE ASSOCIATED WITH fech VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process erythrocyte maturation (more)
    Cellular Component mitochondrion (more)
    Molecular Function ferrochelatase activity (more)
    GO Terms (all 6)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA fech-201 (1) 1431
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM fech No data available
    MARKER RELATIONSHIPS
    fechContained in: [Fosmid] CH1073-334H6 (1) (order this)
    fechEncodes: [cDNA] MGC:109851 (1) (order this), MGC:191894 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131631 (1) 1405bp
    Genomic GenBank:FP245523 (1) 34475bp
    Select Tool
    Polypeptide UniProtKB:F1R362 (1) 409aa
    Sequence Clusters UniGene:82519 (1)
    Sequence Information (all 18)
    ORTHOLOGY for fech (Chr: 21)
    CITATIONS (46)