ZFIN ID: ZDB-GENE-000906-2
Gene Name: heat shock 10 protein 1
Gene Symbol: hspe1    Nomenclature History

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Previous Names: cpn10 (1), zgc:86747

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have chaperone binding activity; metal ion binding activity; and unfolded protein binding activity. Predicted to be involved in chaperone cofactor-dependent protein refolding. Predicted to localize to the mitochondrial matrix. Is expressed in several structures, including alar plate midbrain region; digestive system; midbrain; pectoral fin; and segmental plate. Orthologous to human HSPE1 (heat shock protein family E (Hsp10) member 1).
Genome Resources: Alliance (1),  Gene:58041 (1),  Ensembl(GRCz11):ENSDARG00000056167 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hg76 Small Deletion Unknown Unknown CRISPR
hg77 Small Deletion Unknown Unknown CRISPR
la026912Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la026913Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-hspe1 3
    CRISPR2-hspe1
    2
    PHENOTYPE
    Data: Fig. 2 from Pei et al., 2018
    Observed in:
    DISEASE ASSOCIATED WITH hspe1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hspe1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein folding (more)
    Cellular Component mitochondrial matrix (more)
    Molecular Function chaperone binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR020818 GroES chaperonin family
    Homologous_superfamily IPR011032 GroES-like superfamily
    Homologous_superfamily IPR037124 GroES chaperonin superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hspe1-202 (1)    Ensembl 682
    hspe1-203 (1)    Ensembl 1189
    hspe1-204 (1)    Ensembl 881
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hspe1 No data available
    MARKER RELATIONSHIPS
    hspe1 Contained in: [BAC] DKEY-83M22 (1) (order this)
    hspe1 Encodes: [EST] IMAGE:6898979 (1)
    [cDNA] MGC:86747 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131526 (1) 567 nt
    Genomic GenBank:BX530407 (1) 292409 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q6IQI7 (1) 100 aa
    Sequence Information (all 25)
    ORTHOLOGY for hspe1 ( Chr: 9 )
    CITATIONS (33)