ZFIN ID: ZDB-GENE-000616-4
Gene Name: apoptotic peptidase activating factor 1
Gene Symbol: apaf1    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: zgc:136543

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have cysteine-type endopeptidase activator activity involved in apoptotic process. Predicted to be involved in activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c. Predicted to localize to apoptosome. Orthologous to human APAF1 (apoptotic peptidase activating factor 1).
Genome Resources: Alliance (1),  Gene:58131 (1),  Ensembl(GRCz11):ENSDARG00000021239 (2)
GENE EXPRESSION
All Expression Data: Fig. 2 from Jin et al., 2013
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH apaf1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH apaf1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process apoptotic process (more)
Cellular Component apoptosome (more)
Molecular Function ADP binding (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA apaf1-201 (1)    Ensembl 4533
ncRNA apaf1-003 (1)    Ensembl 647
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM apaf1 No data available
MARKER RELATIONSHIPS
apaf1 Contained in: [BAC] CH211-173P13 (1)
apaf1 Encodes: [cDNA] MGC:92565 (1), MGC:136543 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_131608 (1) 3786 nt
Genomic GenBank:CT025647 (1) 113990 nt
Select Tool
Polypeptide UniProtKB:A5WVJ8 (1) 1261 aa
Sequence Information (all 20)
ORTHOLOGY for apaf1 ( Chr: 4 )
CITATIONS (63)