ZFIN ID: ZDB-GENE-000607-75
Gene Name: NOC2-like nucleolar associated transcriptional repressor
Gene Symbol: noc2l    Nomenclature History

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Previous Names: DKFZP564C186-like (1), id:ibd5110 (1), un-named hi3773, unm hi3773, zgc:195326 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have histone binding activity; repressing transcription factor binding activity; and transcription corepressor activity. Predicted to be involved in negative regulation of histone acetylation; negative regulation of transcription by RNA polymerase II; and ribosomal large subunit biogenesis. Predicted to localize to nucleus. Is expressed in immature eye. Orthologous to human NOC2L (NOC2 like nucleolar associated transcriptional repressor).
Genome Resources: Alliance (1),  Gene:58013 (1),  Ensembl(GRCz11):ENSDARG00000001754 (1)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Kudoh et al., 2001 [ibd5110]
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
PHENOTYPE
Data: 2 figures from 2 publications
Observed in:
DISEASE ASSOCIATED WITH noc2l HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH noc2l VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process negative regulation of histone acetylation (more)
Cellular Component Noc1p-Noc2p complex (more)
Molecular Function histone binding (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA noc2l-202 (1)    Ensembl 2876
noc2l-203 (1)    Ensembl 823
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM noc2l No data available
MARKER RELATIONSHIPS
noc2l Contained in: [BAC] DKEY-98J1 (1) (order this)
noc2l Encodes: [EST] ibd5110
[cDNA] MGC:195326 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001003830 (1) 2318 nt
Genomic GenBank:AL845437 (1) 239084 nt Blast at MegaBLAST
Polypeptide UniProtKB:B3DKM2 (1) 754 aa
Sequence Information (all 30)
ORTHOLOGY for noc2l ( Chr: 23 )
CITATIONS (28)