ZFIN ID: ZDB-GENE-000607-65
Gene Name: Enah/Vasp-like a
Gene Symbol: evla    Nomenclature History

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Previous Names: id:ibd2260, zgc:77388

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have SH3 domain binding activity and profilin binding activity. Predicted to be involved in actin polymerization or depolymerization and positive regulation of actin filament polymerization. Predicted to localize to the cytoskeleton. Is expressed in germ ring; nervous system; polster; solid lens vesicle; and trigeminal placode. Orthologous to human EVL (Enah/Vasp-like).
Genome Resources: Alliance (1),  Gene:58003 (1),  Ensembl(GRCz11):ENSDARG00000035650 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa23115 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23116 Point Mutation Unknown Missense ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH evla HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH evla VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actin nucleation (more)
    Cellular Component cytoskeleton (more)
    Molecular Function actin binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000697 WH1/EVH1 domain
    Homologous_superfamily IPR011993 PH-like domain superfamily
    Domain IPR014885 VASP tetramerisation
    Family IPR017354 Vasodilator-stimulated phosphoprotein/ENA/VASP-like
    Family IPR034319 ENA/VASP-like protein
    Homologous_superfamily IPR038023 VASP tetramerisation domain superfamily
    Homologous_superfamily IPR042180 Intermediate filament, rod domain, coil 1B
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA evla-201 (1)    Ensembl 2366
    evla-204 (1)    Ensembl 731
    ncRNA evla-003 (1) 721
    evla-004 (1) 912
    evla-005 (1) 679
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM evla No data available
    MARKER RELATIONSHIPS
    evla Contained in: [BAC] CH211-156P21 (1), DKEYP-115B3 (1)
    evla Encodes: [EST] ibd2260
    [cDNA] MGC:65883 (1), MGC:77388 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_199519 (1) 2440 bp
    Genomic GenBank:BX546478 (1) 131670 bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8RIU8 (1) 390 aa
    Sequence Information (all 34)
    ORTHOLOGY for evla ( Chr: 17 )
    CITATIONS (20)