ZFIN ID: ZDB-GENE-000607-65
Gene Name: Enah/Vasp-like a
Gene Symbol: evla    Nomenclature History

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Previous Names: id:ibd2260, zgc:77388

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have SH3 domain binding activity and profilin binding activity. Predicted to be involved in actin polymerization or depolymerization and positive regulation of actin filament polymerization. Predicted to localize to cytoskeleton. Is expressed in germ ring; nervous system; polster; solid lens vesicle; and trigeminal placode. Orthologous to human EVL (Enah/Vasp-like).
Genome Resources: Alliance (1),  Gene:58003 (1),  Ensembl(GRCz11):ENSDARG00000035650 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa23115 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23116 Point Mutation Unknown Missense ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH evla HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH evla VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actin nucleation (more)
    Cellular Component cytoskeleton (more)
    Molecular Function actin binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA evla-201 (1)    Ensembl 2366
    evla-204 (1)    Ensembl 731
    ncRNA evla-003 (1)    Ensembl 721
    evla-004 (1)    Ensembl 912
    evla-005 (1)    Ensembl 679
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM evla No data available
    MARKER RELATIONSHIPS
    evla Contained in: [BAC] CH211-156P21 (1), DKEYP-115B3 (1)
    evla Encodes: [EST] ibd2260
    [cDNA] MGC:65883 (1), MGC:77388 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_199519 (1) 2440 nt
    Genomic GenBank:BX546478 (1) 131670 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8RIU8 (1) 390 aa
    Sequence Information (all 34)
    ORTHOLOGY for evla ( Chr: 17 )
    CITATIONS (20)