Community Action Needed: Please respond to the NIH RFI
Gene

adgrl2a

ID
ZDB-GENE-000607-49
Name
adhesion G protein-coupled receptor L2a
Symbol
adgrl2a Nomenclature History
Previous Names
  • lphn2
  • lphn2a
  • id:ibd2808
  • lphn2.1 (1)
  • wu:fb72a08
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and brain development. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and cell surface receptor signaling pathway. Predicted to be located in axon and membrane. Predicted to be integral component of membrane. Predicted to be active in neuron projection. Predicted to be integral component of plasma membrane. Is expressed in brain; eye; and tail bud. Orthologous to human ADGRL2 (adhesion G protein-coupled receptor L2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adgrl2a Human Ortholog
No data available
Associated With adgrl2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017983 GPCR, family 2, secretin-like, conserved site
Domain IPR000203 GPS motif
Domain IPR000922 D-galactoside/L-rhamnose binding SUEL lectin domain
Domain IPR001879 GPCR, family 2, extracellular hormone receptor domain
Domain IPR003112 Olfactomedin-like domain
Domain IPR003334 GPCR, family 2, latrophilin, C-terminal
Domain IPR017981 GPCR, family 2-like
Domain IPR032471 GAIN domain, N-terminal
Family IPR000832 GPCR, family 2, secretin-like
Family IPR003924 GPCR, family 2, latrophilin
Family IPR031240 Latrophilin-2
Homologous_superfamily IPR036445 GPCR family 2, extracellular hormone receptor domain superfamily
Homologous_superfamily IPR043159 D-galactoside/L-rhamnose binding SUEL lectin domain superfamily
Domain Details Per Protein
Protein Length D-galactoside/L-rhamnose binding SUEL lectin domain D-galactoside/L-rhamnose binding SUEL lectin domain superfamily GAIN domain, N-terminal GPCR, family 2, extracellular hormone receptor domain GPCR family 2, extracellular hormone receptor domain superfamily GPCR, family 2, latrophilin GPCR, family 2, latrophilin, C-terminal GPCR, family 2-like GPCR, family 2, secretin-like GPCR, family 2, secretin-like, conserved site GPS motif Latrophilin-2 Olfactomedin-like domain
UniProtKB:F1QPV2 1472
UniProtKB:A0A2R8QF57 1465
UniProtKB:A0A2R8QK81 1416
UniProtKB:A0A0R4IX48 1231
UniProtKB:A0A2R8QN46 1483
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations