ZFIN ID: ZDB-GENE-000607-13
Gene Name: SRY-box transcription factor 5
Gene Symbol: sox5    Nomenclature History

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Previous Names: sox5b (1), id:ibd5067, sb:eu456, si:dkey-215a8.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have transcription regulatory region sequence-specific DNA binding activity. Involved in iridophore differentiation; melanocyte differentiation; and xanthophore differentiation. Predicted to localize to nucleus. Is expressed in several structures, including central nervous system; digestive system; fin; forebrain neural keel; and gonad. Orthologous to human SOX5 (SRY-box transcription factor 5).
Genome Resources: Alliance (1),  Gene:567413 (1),  Ensembl(GRCz11):ENSDARG00000011582 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
i300 Unknown Unknown Unknown ZINC_FINGER_NUCLEASE
i301 Unknown Unknown Unknown ZINC_FINGER_NUCLEASE
la011378Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la015343Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la015344Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la015345Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la024453Tg Transgenic Insertion Unknown Unknown DNA
    la024454Tg Transgenic Insertion Unknown Unknown DNA
    la028982Tg Transgenic Insertion Unknown Unknown DNA
    la028983Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • nub13 Small Deletion Exon 4 Unknown CRISPR
    sa18782 Point Mutation Unknown Splice Site ENU
    sa33439 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33440 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-sox5 1
    PHENOTYPE
    Data: Fig. 6 from Nagao et al., 2018
    Observed in:
    DISEASE ASSOCIATED WITH sox5 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Lamb-Shaffer syndrome 616803
    DISEASE ASSOCIATED WITH sox5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA sox5-201 (1)    Ensembl 5138
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM sox5 No data available
    MARKER RELATIONSHIPS
    sox5 Contained in: [BAC] CH211-47D3 (1), DKEY-215A8 (1) (order this)
    sox5 Encodes: [EST] eu456 (1), ibd5067
    [cDNA] MGC:194960 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001033585 (1) 2393 nt
    Genomic GenBank:BX547928 (1) 228177 nt Blast at MegaBLAST
    Polypeptide UniProtKB:B3DJE0 (1) 759 aa
    Sequence Information (all 47)
    ORTHOLOGY for sox5 ( Chr: 4 )
    CITATIONS (44)