ZFIN ID: ZDB-GENE-000607-1
Gene Name: protocadherin 18a
Gene Symbol: pcdh18a    Nomenclature History

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Previous Name: id:ibd5114 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity. Involved in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell migration involved in gastrulation; and epiboly involved in gastrulation with mouth forming second. Localizes to plasma membrane. Is expressed in several structures, including axis; epiblast; midbrain neural keel; nervous system; and spinal cord neural rod. Orthologous to human PCDH18 (protocadherin 18).
Genome Resources: Alliance (1),  Gene:572532 (1),  Ensembl(GRCz11):ENSDARG00000089805 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa9402 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10805 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32619 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45066 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko275a Indel Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • zko275b Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-pcdh18a 1
    MO1-pcdh18a N/A 1
    MO2-pcdh18a N/A 2
    DISEASE ASSOCIATED WITH pcdh18a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pcdh18a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (more)
    Cellular Component plasma membrane (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pcdh18a No data available
    MARKER RELATIONSHIPS
    pcdh18a Encodes: [EST] ibd5114
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001115058 (1) 4443 nt
    Polypeptide UniProtKB:F1QRP2 (1) 1135 aa
    Sequence Information (all 20)
    ORTHOLOGY for pcdh18a ( Chr: 1 )
    CITATIONS (24)