Gene

fbxw4

ID
ZDB-GENE-000516-1
Name
F-box and WD repeat domain containing 4
Symbol
fbxw4 Nomenclature History
Previous Names
  • dac
  • dactylaplasia
  • fk63g06
  • hag (1)
  • hagoromo (1)
  • wu:fk63g06
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to localize to SCF ubiquitin ligase complex. Human ortholog(s) of this gene implicated in split hand-foot malformation 3. Orthologous to human FBXW4 (F-box and WD repeat domain containing 4).
Genome Resources
Note
None
Expression
All Expression Data
5 figures from 5 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fbxw4 Human Ortholog
No data available
Associated With fbxw4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001810 F-box domain
Domain IPR017986 WD40-repeat-containing domain
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036047 F-box-like domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Domain Details Per Protein
Protein Length F-box domain F-box-like domain superfamily WD40 repeat WD40-repeat-containing domain WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:Q9IBH3 392
UniProtKB:Q9IB68 253
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations