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ZIRC
ZFIN ID: ZDB-GENE-000509-3
Gene Name: SMAD family member 3a
Gene Symbol: smad3a
Sequence Ontology ID : SO:0000704

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Previous Names: madh3a, smad3 (1), wu:fa99e03

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(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits sequence-specific DNA binding activity. Involved in mesoderm development; primitive hemopoiesis; and regulation of transcription, DNA-templated. Predicted to localize to the cytoplasm;  ...
GENE EXPRESSION
All Expression Data: 6 figures from 5 publications
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa2363 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34112 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH smad3a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Loeys-Dietz syndrome 3 Loeys-Dietz syndrome 3 613795
    DISEASE ASSOCIATED WITH smad3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component cytoplasm (more)
    Molecular Function protein binding (more)
    GO Terms (all 11)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA smad3a-201 (1) 6173
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM smad3a No data available
    MARKER RELATIONSHIPS
    smad3aContained in: [BAC] DKEY-34G19 (1) (order this)
    smad3aEncodes: [EST] fa99e03
    [cDNA] MGC:158174 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131571 (1) 2702bp
    Genomic GenBank:CR927368 180874bp
    Select Tool
    Polypeptide UniProtKB:Q8AY15 (1) 425aa
    Sequence Clusters UniGene:87309 (1)
    Sequence Information (all 17)
    ORTHOLOGY for smad3a (Chr: 7)
    CITATIONS (44)