ZFIN ID: ZDB-GENE-000411-1
Gene Name: wingless-type MMTV integration site family, member 4b
Gene Symbol: wnt4b    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have cytokine activity and frizzled binding activity. Involved in negative regulation of mitotic nuclear division. Predicted to localize to extracellular space. Is expressed in blastomere; brain; ciliary marginal zone; and floor plate.
Genome Resources: Alliance (1),  Gene:791993 (1),  Ensembl(GRCz11):ENSDARG00000040159 (1)
Note: Mammalian orthologs removed from record 20 May, 2019. Zebrafish wnt4 is the only ortholog of human WNT4 in zebrafish. Teleost wnt4b is a VGD ohnolog gone missing from humans. Teleosts, gar, coelacanth, and some birds and lizard have orthologs of both wnt4a and wnt4b
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-wnt4b N/A 1
MO2-wnt4b N/A 1
DISEASE ASSOCIATED WITH wnt4b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH wnt4b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of mitotic nuclear division (more)
Cellular Component extracellular region (more)
Molecular Function signaling receptor binding (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA wnt4b-202 (1)    Ensembl 2210
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM wnt4b No data available
MARKER RELATIONSHIPS
wnt4b Contained in: [BAC] CH211-57K11 (1)
wnt4b Encodes: [cDNA] MGC:193624 (1), MGC:193639 (1), MGC:193748 (1), MGC:193777 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_131500 (1) 2260 nt
Genomic GenBank:BX511250 (1) 189081 nt
Select Tool
Polypeptide UniProtKB:A0A0B5JQ72 (1) 358 aa
Sequence Information (all 27)
ORTHOLOGY for wnt4b ( Chr: 16 )
CITATIONS (33)