Gene

wnt4b

ID
ZDB-GENE-000411-1
Name
wingless-type MMTV integration site family, member 4b
Symbol
wnt4b Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have cytokine activity and frizzled binding activity. Involved in negative regulation of mitotic nuclear division. Predicted to localize to extracellular space. Is expressed in blastomere; brain; ciliary marginal zone; and floor plate.
Genome Resources
Note
Mammalian orthologs removed from record 20 May, 2019. Zebrafish wnt4 is the only ortholog of human WNT4 in zebrafish. Teleost wnt4b is a VGD ohnolog gone missing from humans. Teleosts, gar, coelacanth, and some birds and lizard have orthologs of both wnt4a and wnt4b
Comparative Information
Expression
All Expression Data
12 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Zhong et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With wnt4b Human Ortholog
No data available
Associated With wnt4b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018161 Wnt protein, conserved site
Family IPR005817 Wnt
Homologous_superfamily IPR043158 Wnt, C-terminal domain
Domain Details Per Protein
Protein Length Wnt Wnt, C-terminal domain Wnt protein, conserved site
UniProtKB:Q9IAU3 358
UniProtKB:A0A0B5JQ72 358
UniProtKB:F6NGJ7 358
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations