ZFIN is now using GRCz12tu for Genomic Data
Gene
cdc25b
- ID
- ZDB-GENE-000330-5
- Name
- cell division cycle 25B
- Symbol
- cdc25b Nomenclature History
- Previous Names
-
- cdc25
- cdc25a (1)
- sb:cb317
- sds
- standstill
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable protein tyrosine phosphatase activity. Acts upstream of or within positive regulation of mitotic cell cycle; regulation of G2/M transition of mitotic cell cycle; and regulation of mitotic cell cycle, embryonic. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including DEL; anterior neural keel; axis; nervous system; and optic vesicle. Human ortholog(s) of this gene implicated in autosomal recessive polycystic kidney disease; cervical cancer; endometrial cancer; prostate cancer; and urinary bladder cancer. Orthologous to several human genes including CDC25B (cell division cycle 25B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb317 (33 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | M-phase inducer phosphatase | Rhodanese-like domain | Rhodanese-like domain superfamily |
|---|---|---|---|---|---|
| UniProtKB:B8A5N7 | InterPro | 563 | |||
| UniProtKB:B5LY73 | InterPro | 562 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cdc25b-201
(1)
|
Ensembl | 3,104 nt | ||
| mRNA |
cdc25b-202
(1)
|
Ensembl | 412 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers