Gene

cdc25b

ID
ZDB-GENE-000330-5
Name
cell division cycle 25B
Symbol
cdc25b Nomenclature History
Previous Names
  • cdc25
  • cdc25a (1)
  • sb:cb317
  • sds
  • standstill
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have protein tyrosine phosphatase activity. Involved in positive regulation of mitotic cell cycle; regulation of G2/M transition of mitotic cell cycle; and regulation of mitotic cell cycle, embryonic. Predicted to localize to cytoplasm and nucleus. Is expressed in several structures, including DEL; anterior neural keel; axis; nervous system; and optic vesicle. Human ortholog(s) of this gene implicated in autosomal recessive polycystic kidney disease; cervical cancer; endometrial cancer; prostate cancer; and urinary bladder cancer. Orthologous to several human genes including CDC25B (cell division cycle 25B).
Genome Resources
Note
None
Expression
All Expression Data
13 figures from 6 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cdc25b Human Ortholog
No data available
Associated With cdc25b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001763 Rhodanese-like domain
Family IPR000751 M-phase inducer phosphatase
Homologous_superfamily IPR036873 Rhodanese-like domain superfamily
Domain Details Per Protein
Protein Length M-phase inducer phosphatase Rhodanese-like domain Rhodanese-like domain superfamily
UniProtKB:B8JKA6 122
UniProtKB:Q9IAA8 142
UniProtKB:B5LY73 562
UniProtKB:B8A5N7 563
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations