ZFIN ID: ZDB-GENE-000329-9
Gene Name: actinin alpha 3a
Gene Symbol: actn3a
Sequence Ontology ID : SO:0000704

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Previous Names: actn3 (1), actnl, zgc:63559

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(Including Attributions)
Location: Chr: 21 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 15 figures from 5 publications
Directly Submitted Expression Data: 6 figures (11 images) from Thisse et al., 2004 [IMAGE:7148639]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  adaxial cell, adductor hyohyoid, adductor operculi, inferior hyohyoid (all 25) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa13372 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43661 Point Mutation Unknown Splice Site ENU
    Targeting reagents: MO1-actn3a (1)
    PHENOTYPE
    Data: Fig. 6 from Frese et al., 2015
    Observed in: atrium, blood circulation, cardiac ventricle, heart
    DISEASE ASSOCIATED WITH actn3a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    [Alpha-actinin-3 deficiency]
    [Sprinting performance]
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component cellular_component (more)
    Molecular Function actin binding (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001589
  • InterPro:IPR001715
  • InterPro:IPR002017
  • InterPro:IPR002048
  • InterPro:IPR011992
  • InterPro:IPR014837
  • InterPro:IPR018159
  • PROSITE:PS00019
  • PROSITE:PS00020
  • PROSITE:PS50021
  • PROSITE:PS50222
  • Pfam:PF00307
  • Pfam:PF00435
  • Pfam:PF08726
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA actn3a-001 (1) 3259
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM actn3a No data available
    MARKER RELATIONSHIPS
    actn3aContained in: [BAC] DKEY-197A18 (1) (order this)
    actn3aEncodes: [EST] IMAGE:7148639 (1) (order this)
    [cDNA] MGC:63559 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131522 (1) 3209bp
    Genomic GenBank:BX511175 (1) 134295bp
    Select Tool
    Polypeptide UniProtKB:D1GJ56 896aa
    Sequence Clusters UniGene:78193 (1)
    Sequence Information (all 19)
    OTHER actn3a GENE PAGES
  • Gene:58037 (1)
  • VEGA:OTTDARG00000021045 (1)
  • Ensembl(GRCz10):ENSDARG00000013755 (1)
  • ORTHOLOGY for actn3a (Chr: 21)
    CITATIONS (21)