ZFIN ID: ZDB-GENE-000329-9
Gene Name: actinin alpha 3a
Gene Symbol: actn3a    Nomenclature History

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Previous Names: actn3 (1), actnl, zgc:63559

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have actin filament binding activity and calcium ion binding activity. Predicted to be involved in actin crosslink formation and actin filament bundle assembly. Is expressed in several structures, including musculature system; ovary; pectoral fin; pharyngeal arch 3-7; and segmental plate. Orthologous to human ACTN3 (actinin alpha 3).
Genome Resources: Alliance (1),  Gene:58037 (1),  Ensembl(GRCz11):ENSDARG00000013755 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa13372 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43661 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-actn3a N/A 1
    DISEASE ASSOCIATED WITH actn3a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    [Alpha-actinin-3 deficiency] 617749
    [Sprinting performance] 617749
    DISEASE ASSOCIATED WITH actn3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actin crosslink formation (more)
    Cellular Component cellular_component (more)
    Molecular Function actin binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA actn3a-201 (1)    Ensembl 3259
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM actn3a No data available
    MARKER RELATIONSHIPS
    actn3a Contained in: [BAC] DKEY-197A18 (1) (order this)
    actn3a Encodes: [EST] IMAGE:7148639 (1)
    [cDNA] MGC:63559 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131522 (1) 3210 nt
    Genomic GenBank:BX511175 (1) 134295 nt
    Select Tool
    Polypeptide UniProtKB:D1GJ56 (1) 896 aa
    Sequence Information (all 19)
    ORTHOLOGY for actn3a ( Chr: 21 )
    CITATIONS (27)