Gene

actn3a

ID
ZDB-GENE-000329-9
Name
actinin alpha 3a
Symbol
actn3a Nomenclature History
Previous Names
  • actn3 (1)
  • actnl
  • zgc:63559
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity and calcium ion binding activity. Predicted to be involved in actin crosslink formation and actin filament bundle assembly. Is expressed in several structures, including musculature system; ovary; pectoral fin; pharyngeal arch 3-7; and segmental plate. Orthologous to human ACTN3 (actinin alpha 3 (gene/pseudogene)).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
16 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Frese et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With actn3a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
[Alpha-actinin-3 deficiency] 617749
[Sprinting performance] 617749
Associated With actn3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR001589 Actinin-type actin-binding domain, conserved site
Domain IPR001715 Calponin homology domain
Domain IPR002048 EF-hand domain
Domain IPR014837 EF-hand, Ca insensitive
Homologous_superfamily IPR011992 EF-hand domain pair
Homologous_superfamily IPR036872 CH domain superfamily
Repeat IPR002017 Spectrin repeat
Repeat IPR018159 Spectrin/alpha-actinin
Domain Details Per Protein
Protein Length Actinin-type actin-binding domain, conserved site Calponin homology domain CH domain superfamily EF-hand, Ca insensitive EF-hand domain EF-hand domain pair Spectrin/alpha-actinin Spectrin repeat
UniProtKB:D1GJ56 896
UniProtKB:O73760 53
UniProtKB:Q7SYD3 896
UniProtKB:Q6TNW2 896
UniProtKB:A0A2R8Q5Z6 885
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations