ZFIN ID: ZDB-GENE-000329-9
Gene Name: actinin alpha 3a
Gene Symbol: actn3a
Previous Names: actn3 (1), actnl, zgc:63559
Location: Chr: 21 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 15 figures from 5 publications
Directly Submitted Expression Data: 6 figures (11 images) from Thisse et al., 2004 [IMAGE:7148639]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  adaxial cell, adductor hyohyoid, adductor operculi, inferior hyohyoid (all 25) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
sa13372 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-actn3a (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH actn3a HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    [Sprinting performance]
    [Alpha-actinin-3 deficiency]
    GENE ONTOLOGY 
    Ontology GO Term
    Cellular Component cellular_component (more)
    Molecular Function actin binding (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001589 (1)
  • InterPro:IPR001715 (1)
  • InterPro:IPR002017 (1)
  • InterPro:IPR002048 (1)
  • InterPro:IPR011992 (1)
  • InterPro:IPR014837 (1)
  • InterPro:IPR018159 (1)
  • PROSITE:PS00019 (1)
  • PROSITE:PS00020 (1)
  • PROSITE:PS50021 (1)
  • PROSITE:PS50222 (1)
  • Pfam:PF00307 (1)
  • Pfam:PF00435 (1)
  • Pfam:PF08726 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA actn3a-001 (1) 3259
    GENE PRODUCT DESCRIPTION No description available
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM actn3a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    actn3aContained in: [BAC] DKEY-197A18 (1) (order this)
    actn3aEncodes: [EST] IMAGE:7148639 (1) (order this)
    [cDNA] MGC:63559 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131522 (1) 3209bp
    Genomic GenBank:BX511175 (1) 134295bp
    Select Tool
    Polypeptide UniProtKB:D1GJ56 (1) 896aa
    Sequence Clusters UniGene:78193 (1)
    Sequence Information (all 18)
    OTHER actn3a GENE PAGES 
  • Gene:58037 (1)
  • VEGA:OTTDARG00000021045 (1)
  • Ensembl(GRCz10):ENSDARG00000013755 (1)
  • ORTHOLOGY for actn3a (Chr: 21) 
    Species Symbol Chromosome Accession # Evidence
    Human ACTN3 11
  • Gene:89
  • OMIM:102574
  • HGNC:165
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (1)
    Mouse Actn3 19
  • MGI:99678
  • Gene:11474
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (21)